Lo Kirk C, Whirledge Shannon, Lamb Dolores J
Department of Urology, Baylor College of Medicine, One Baylor Plaza, Alkek N 730, Houston, TX 77030, USA.
Curr Urol Rep. 2005 Feb;6(1):49-54. doi: 10.1007/s11934-005-0067-5.
Stem cells are characterized by their potential immortality and are capable of self-renewal and differentiation. Stem cells are proposed to provide the potential to cure degenerative diseases and to give important clues regarding human development and aging. However, stem cell research has evoked enthusiasm and passionate debate regarding the ethics of their use in medicine and reproduction. In this article, the current understanding of the biology of stem cells, their application in urology, and some of the controversies regarding their use are discussed. Although the clinical application of stem cell technologies to urologic practice is likely to be well in the future, advances in this field hold great promise for the correction of a number of illnesses. Nevertheless, scientists and ethicists will continue to struggle with their ethical responsibilities to the patient and society.
干细胞的特点是具有潜在的永生能力,能够自我更新和分化。有人提出干细胞具有治愈退行性疾病的潜力,并能为人类发育和衰老提供重要线索。然而,干细胞研究引发了关于其在医学和生殖领域应用的伦理问题的热烈讨论和激烈辩论。本文讨论了目前对干细胞生物学的理解、它们在泌尿外科的应用以及一些关于其使用的争议。尽管干细胞技术在泌尿外科临床实践中的应用可能还很遥远,但该领域的进展有望纠正许多疾病。尽管如此,科学家和伦理学家将继续为他们对患者和社会的伦理责任而努力。