Hyett Jon
Harris Birthright Research Centre for Fetal Medicine, King's College Hospital, Denmark Hill, London UK.
Prenat Diagn. 2004 Dec 30;24(13):1130-5. doi: 10.1002/pd.1070.
Increased nuchal translucency is the strongest single marker for chromosomal abnormality. Consequently, it is currently becoming established as the foundation of most early screening programmes for Down syndrome. In the absence of chromosomal abnormality, increased nuchal translucency has been shown to be associated with other congenital anomalies including cardiac defects. Several datasets have now reported this association and here these are reviewed to assess the effectiveness of nuchal translucency measurement as a screening tool for the prenatal detection of congenital heart disease.
颈后透明带增厚是染色体异常最强的单一标志物。因此，它目前正成为大多数唐氏综合征早期筛查项目的基础。在不存在染色体异常的情况下，颈后透明带增厚已被证明与包括心脏缺陷在内的其他先天性异常有关。现在有几个数据集报告了这种关联，在此对这些数据集进行综述，以评估颈后透明带测量作为先天性心脏病产前检测筛查工具的有效性。
