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[生化汤提取物对妊娠晚期家兔子宫肌电活动的影响]

[Effect of extract from shenghua decoction on myoelectric activity of rabbit uterine muscle in the latest period of pregnancy].

作者信息

Hong Min, Yu Li, Ma Cheng, Zhu Quan

机构信息

National Standard Lab of Pharmacology for Chinese Materia Medica, Nanjing 210029, Jiangsu, China.

出版信息

Zhongguo Zhong Yao Za Zhi. 2003 Dec;28(12):1162-4.

Abstract

OBJECTIVE

To elucidate the difference between uterus body and cervix under the intervention of Shenghua decoction, and to observe the rabbit uterine muscle in the latest period of pregnancy for the way of myoelectric activity.

METHOD

PowerLab/8s was used to record myoelectric activity of rabbit muscle in uterus body and cervix which was in a general anaesthesia state induced by urethane.

RESULT

Myoelectric activities of rabbit uterine smooth muscle in the latest period of pregnancy was enhanced in vivo by being treated with Shenghua decoction 40 mg x kg(-1) (P < 0.01) while cervix myoelectric activities had no significant change (P < 0.05).

CONCLUSION

Myoelectric activities of rabbit uterine muscle in the latest period of pregnancy are enhanced by being treated with Shenghua decoction so its hemostatic effect can be represented via the constriction of uterus body. Shenghua decoction is beneficial for child delivery because cervix myoelectric activities have no significant change under the intervention of Shenghua decoction while the myoelectric activities of uterus body are increased significantly.

摘要

目的

阐明生化汤干预下子宫体与宫颈的差异,观察妊娠末期家兔子宫肌电活动情况。

方法

采用PowerLab/8s记录在氨基甲酸乙酯诱导的全身麻醉状态下家兔子宫体和宫颈肌肉的肌电活动。

结果

妊娠末期家兔子宫平滑肌经40mg·kg⁻¹生化汤处理后,肌电活动增强(P<0.01),而宫颈肌电活动无明显变化(P<0.05)。

结论

妊娠末期家兔子宫肌经生化汤处理后肌电活动增强,其止血作用可通过子宫体收缩体现。生化汤对分娩有益,因为在生化汤干预下宫颈肌电活动无明显变化,而子宫体肌电活动显著增加。

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