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一种藻类冰结合蛋白减少冻融诱导的红细胞溶血

Reduction of freeze-thaw-induced hemolysis of red blood cells by an algal ice-binding protein.

作者信息

Kang Jae-Shin, Raymond James A

机构信息

Department of Biological Sciences, University of Nevada, Las Vegas 89154, USA.

出版信息

Cryo Letters. 2004 Sep-Oct;25(5):307-10.

PMID:15618982
Abstract

Antarctic sea ice diatoms produce ice-binding proteins (IBPs) that are strong inhibitors of the recrystallization of ice. Their function may be to reduce cell damage in the frozen state. We show here that an IBP from the diatom Navicula glaciei Vanheurck also has the ability to reduce freeze-thaw damage to red blood cells and that the effect may be due to its ability to inhibit recrystallization of ice.

摘要

南极海冰硅藻会产生冰结合蛋白(IBP),这些蛋白是冰重结晶的强效抑制剂。它们的功能可能是减少细胞在冷冻状态下受到的损伤。我们在此表明,来自硅藻冰川舟形藻(Navicula glaciei Vanheurck)的一种冰结合蛋白也有减少红细胞冻融损伤的能力,且这种效果可能归因于其抑制冰重结晶的能力。

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