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隐匿性系统性肥大细胞增多症中的类过敏反应。一种罕见的皮肤科急症

[Anaphylactoid reaction in occult systemic mastocytosis. A rare dermatologic emergency ].

作者信息

Ständer H, Beier K, Metze D, Brehler R

机构信息

Klinik und Poliklinik für Hautkrankheiten, Universitätsklinikum Münster.

出版信息

Hautarzt. 2005 Mar;56(3):265-9. doi: 10.1007/s00105-004-0820-6.

Abstract

With the occurrence of unclear consciousness conditions primarily internal or neurological causes are considered. Of a systemic mastocytosis one thinks only rarely, which can accompany without or with slight clinically visible skin changes. In the following we report on a patient who has repeated unclear shock conditions and required resuscitation several times without a recognizable cause, with whom a systemic mastocytosis could be proven. Clinically very discrete lesions of mastocytosis were recognizable from the skin. Only an increased tryptase level referred to being present an occult systemic mastocytosis. The diagnostics, potential triggers and therapy of this disease are to be discussed on the basis the available case.

摘要

当出现意识不清的情况时,主要考虑内部或神经方面的原因。系统性肥大细胞增多症很少被想到,它可以在没有或仅有轻微临床可见皮肤变化的情况下伴随出现。以下我们报告一例患者,该患者反复出现不明原因的休克状态,多次需要进行复苏且原因不明,最终证实其患有系统性肥大细胞增多症。临床上从皮肤上可识别出非常轻微的肥大细胞增多症病变。只有血清类胰蛋白酶水平升高提示存在隐匿性系统性肥大细胞增多症。将基于现有病例讨论该疾病的诊断、潜在触发因素和治疗方法。

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