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Comparison of quantitative angiographic parameters with the magnitude of neointimal hyperplasia measured by volumetric intravascular ultrasound in patients treated with bare metal and nonpolymeric paclitaxel-coated stents.

作者信息

Mintz Gary S, Hong Myeong-Ki, Raizner Albert E, Lee Cheol Whan, Kim Jae-Joong, Escolar Esteban, Fearnot Neal E, Park Seong-Wook, Park Seung-Jung, Weissman Neil J

机构信息

Department of Medicine, University of Ulsan College of Medicine, Seoul, Korea.

出版信息

Am J Cardiol. 2005 Jan 1;95(1):105-7. doi: 10.1016/j.amjcard.2004.08.071.

DOI:10.1016/j.amjcard.2004.08.071
PMID:15619403
Abstract

We used data from the ASian Paclitaxel-Eluting Stent Clinical Trial (a 3-center, randomized, placebo-controlled trial of nonpolymeric paclitaxel-coated stents with a single-center intravascular ultrasound substudy) to compare angiographic indexes of drug-eluting stent efficacy with the magnitude of intimal hyperplasia (IH) assessed by intravascular ultrasound. Overall, percent IH (IH volume divided by stent volume) was larger in restenotic lesions than in nonrestenotic lesions (46 +/- 19% vs 15 +/- 13%, p <0.0001); angiographic late loss and follow-up diameter stenoses correlated strongly with percent IH.

摘要

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