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乳腺钼靶筛查性能指标的国际比较:可行吗?

International comparison of performance measures for screening mammography: can it be done?

作者信息

Yankaskas B C, Klabunde C N, Ancelle-Park R, Renner G, Wang H, Fracheboud J, Pou G, Bulliard J-L

机构信息

Department of Radiology, University of North Carolina, Chapel Hill, 27599-7515, USA.

出版信息

J Med Screen. 2004;11(4):187-93. doi: 10.1258/0969141042467430.

Abstract

OBJECTIVE

Published screening mammography performance measures vary across countries. An inter-national study was undertaken to assess the comparability of two performance measures: the recall rate and positive predictive value (PPV). These measures were selected because they do not require identification of all cancers in the screening population, which is not always possible.

SETTING

The screening mammography programs or data registries in 25 member countries of the International Breast Cancer Screening Network (IBSN).

METHODS

In 1999 an assessment form was distributed to IBSN country representatives in order to obtain information on how screening mammography was performed and what specific data related to recall rates and PPV were collected. Participating countries were then asked to provide data to allow calculation of recall rates, PPV and cancer detection rates for screening mammography by age group for women screened in the period 1997-1999.

RESULTS

Twenty-two countries completed the assessment form and 14 countries provided performance data. Differences in screening mammography delivery and data collection were evident. For most countries, recall rates were higher for initial than for subsequent mammograms. There was no consistent relationship of initial to subsequent PPV, although PPV generally decreased as the recall rate increased. Recall rates decreased with increasing age, while PPV increased as age increased.

CONCLUSION

Similar patterns for mammography performance measures were evident across countries.However, the development of a more standardized approach to defining and collecting data would allow more valid international comparisons, with the potential to optimize mammography performance. At present, international comparisons of performance should be made with caution due to differences in defining and collecting mammography data.

摘要

目的

各国公布的乳腺钼靶筛查性能指标各不相同。开展了一项国际研究,以评估两项性能指标的可比性:召回率和阳性预测值(PPV)。选择这些指标是因为它们不需要识别筛查人群中的所有癌症,而这并非总是可行的。

背景

国际乳腺癌筛查网络(IBSN)25个成员国的乳腺钼靶筛查项目或数据登记处。

方法

1999年向IBSN国家代表分发了一份评估表,以获取有关乳腺钼靶筛查如何进行以及收集了哪些与召回率和PPV相关的具体数据的信息。随后要求参与国家提供数据,以便计算1997 - 1999年期间接受筛查的女性按年龄组划分的乳腺钼靶筛查召回率、PPV和癌症检出率。

结果

22个国家完成了评估表,14个国家提供了性能数据。乳腺钼靶筛查实施和数据收集方面的差异很明显。对于大多数国家,初次乳腺钼靶检查的召回率高于后续检查。初次与后续PPV之间没有一致的关系,尽管PPV通常随着召回率的增加而降低。召回率随年龄增加而降低,而PPV随年龄增加而增加。

结论

各国乳腺钼靶筛查性能指标的模式相似。然而,制定一种更标准化的定义和收集数据的方法将有助于进行更有效的国际比较,有可能优化乳腺钼靶筛查性能。目前,由于乳腺钼靶数据定义和收集方面的差异,进行国际性能比较时应谨慎。

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