Allin Steven M, Thomas Christopher I, Doyle Kevin, Elsegood Mark R J
Department of Chemistry, Loughborough University, Loughborough, Leicestershire, LE11 3TU, England.
J Org Chem. 2005 Jan 7;70(1):357-9. doi: 10.1021/jo040245k.
We report a novel, facile and asymmetric approach to both enantiomers of the indole alkaloid deplancheine from a readily available, nonracemic chiral template. The natural product and its antipode are isolated with >95% ee.
我们报道了一种新颖、简便且不对称的方法，可从一种易于获得的非外消旋手性模板出发，合成吲哚生物碱去普兰琴的对映体。天然产物及其对映体的分离对映体过量值（ee）>95%。
