Arrich Jasmin, Lalouschek Wolfgang, Müllner Marcus
Department of Emergency Medicine, Medical University of Vienna, Vienna General Hospital, Vienna, Austria.
Stroke. 2005 Feb;36(2):310-4. doi: 10.1161/01.STR.0000152962.92621.b5. Epub 2004 Dec 29.
Low socioeconomic status is associated with increased morbidity and mortality from stroke. The purpose of this study was to investigate the association between 4 independent measures of socioeconomic status and mortality of patients with acute ischemic stroke and transient ischemic attack.
Socioeconomic status was assessed by taking into account levels of education, occupation, occupational status, and income. The end point was overall mortality. We used Cox proportional hazard models to adjust for age, sex, and severity of stroke on admission.
A total of 2606 stroke patients were followed up for a median of 2.5 years. Unskilled workers had a hazard ratio of 1.87 for death after stroke (95% CI, 1.37 to 2.55) and skilled workers had a hazard ratio of 1.61 (95% CI, 1.23 to 2.11) compared with white-collar workers. Of 4 income groups, patients with the second lowest level of income had a hazard ratio of 1.60 (95% CI, 1.10 to 2.33) and patients with the third lowest level of income had a hazard ratio of 1.71 (95% CI, 1.25 to 2.32) compared with patients with the highest income. The hazard ratio for death after stroke for early retired patients was 1.75 (95% CI, 1.01 to 3.04) compared with stroke patients in the active workforce at the time of the event.
Socioeconomic status is associated with survival of patients with acute stroke after adjustment for age, sex, and severity of stroke. The influence of socioeconomic status seems to continue to affect the outcome largely independent of stroke severity.
社会经济地位低下与中风发病率和死亡率的增加相关。本研究的目的是调查社会经济地位的4项独立指标与急性缺血性中风和短暂性脑缺血发作患者死亡率之间的关联。
通过考虑教育水平、职业、职业地位和收入来评估社会经济地位。终点是全因死亡率。我们使用Cox比例风险模型对年龄、性别和入院时中风严重程度进行校正。
共对2606例中风患者进行了中位时间为2.5年的随访。与白领相比,非技术工人中风后死亡的风险比为1.87(95%CI,1.37至2.55),技术工人的风险比为1.61(95%CI,1.23至2.11)。在4个收入组中,与收入最高的患者相比,收入第二低水平的患者风险比为1.60(95%CI,1.10至2.33),收入第三低水平的患者风险比为1.71(95%CI,1.25至2.32)。与事件发生时在职的中风患者相比,提前退休患者中风后死亡的风险比为1.75(95%CI,1.01至3.04)。
在对年龄、性别和中风严重程度进行校正后,社会经济地位与急性中风患者的生存相关。社会经济地位的影响似乎在很大程度上独立于中风严重程度而继续影响预后。