Gafarov V V, Gromova E A, Gagulin I V, Pilipenko P I
Zh Nevrol Psikhiatr Im S S Korsakova. 2004(Suppl 12):40-5.
An aim of the study was to investigate the influence of psychosocial factors on risk of stroke development during 16 years in men aged 25-64 years. Three scanning population surveys (1984, 1988, 1994) have been conducted in the frame of the WHO program "MONICA-psychosocial". Men at the age of 25-64 years, dwelling in a district of Novosibirsk city, were studied during a control period of 1984-2000. Statistical analysis was performed using SPPS-10 statistical package. Cox-proportional regression model was used for relative risk evaluation. The highest percentage of patients with stroke was found in the older group of 55-64 years. A distribution of personality anxiety level in men who survived stroke was as follows: 72.2% with high anxiety level and 27.8%-with a moderate one. The highest relative risk of stroke was observed in men with high anxiety, who related to the following groups: widowed and divorced; with primary and not-completed secondary school education; pensioners and those engaged in hard and moderate manual labor. The highest relative risk was during the first 5 years, being 6.8 times higher in subjects with higher anxiety level than in those with moderate level. For the following 10 years, relative risk was 5 times higher in men with high level of anxiety and after 16 years it was 3 times higher than in those with moderate anxiety level. The results obtained suggest that stroke most often develops at age of 55-64 years; its risk is associated with social gradient and is highest in the first 5 years. To prevent stroke, conditions reducing an impact of psychosocial factors on population are needed.
该研究的一个目的是调查心理社会因素对25至64岁男性16年间中风发病风险的影响。在世界卫生组织“MONICA-心理社会”项目框架内进行了三次扫描人群调查（1984年、1988年、1994年）。对居住在新西伯利亚市一个区的25至64岁男性在1984 - 2000年的对照期内进行了研究。使用SPPS - 10统计软件包进行统计分析。采用Cox比例回归模型评估相对风险。中风患者比例最高的是55至64岁的老年组。中风幸存者中男性的人格焦虑水平分布如下：高焦虑水平者占72.2%，中度焦虑水平者占27.8%。焦虑程度高的男性中风相对风险最高，这些男性包括以下几类：丧偶和离异者；小学及未完成中学教育者；退休人员以及从事重体力和中等体力劳动者。最高相对风险出现在头5年，焦虑水平较高的受试者比中度焦虑水平的受试者高6.8倍。在接下来的10年里，焦虑水平高的男性相对风险高5倍，16年后比中度焦虑水平者高3倍。所得结果表明，中风最常发生在55至64岁；其风险与社会梯度相关，且在头5年最高。为预防中风，需要创造减少心理社会因素对人群影响的条件。
