Bisschop S P R, van Vuuren M, Gummow B
Department of Production Animal Studies, Faculty of Veterinary Science, University of Pretoria, Private Bag X04, Onderstepoort, South Africa.
J S Afr Vet Assoc. 2004 Sep;75(3):125-8. doi: 10.4102/jsava.v75i3.467.
Ornithobacterium rhinotracheale (ORT) is a recently identified bacterial pathogen of poultry, linked to the respiratory disease complex of broilers and the economic losses associated with that disease complex. Present control measures applied for the disease include the continuous use of in-feed antibiotics. A recently developed bacterin vaccine that is applied to broiler-breeder hens to pass on protective immunity to their broiler progeny was tested under large-scale commercial conditions in South Africa. An indirect ELISA test for antibodies to ORT, optimised for use in South Africa, was used to determine antibody levels in breeders and broilers. ELISA test results showed that the vaccine stimulated the development of high antibody titre levels in broiler breeders. The efficacy of the vaccine in protecting the progeny of these birds from ORT challenge could not be determined during the trial, although the progeny of vaccinated hens appeared to perform slightly better under commercial conditions than the progeny of unvaccinated hens.
禽气管鸟杆菌（ORT）是一种最近才被确认的家禽细菌性病原体，与肉鸡呼吸道疾病综合症以及该疾病综合症相关的经济损失有关。目前针对该疾病采取的控制措施包括持续使用饲料中添加的抗生素。一种最近研发的菌苗疫苗应用于肉种鸡，以使它们的肉鸡后代获得保护性免疫力，该疫苗在南非的大规模商业条件下进行了测试。一种针对南非使用情况进行优化的间接ELISA检测方法，用于测定种鸡和肉鸡中的抗体水平。ELISA检测结果表明，该疫苗刺激肉种鸡产生了高抗体滴度水平。尽管接种疫苗的母鸡所产后代在商业条件下似乎比未接种疫苗的母鸡所产后代表现略好，但在试验期间无法确定该疫苗保护这些鸡后代免受ORT攻击的效果。
