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马拉色菌毛囊炎:6例寻常痤疮女性青少年患者的诊断与治疗

Pityrosporum folliculitis: diagnosis and management in 6 female adolescents with acne vulgaris.

作者信息

Ayers Katherine, Sweeney Susan M, Wiss Karen

机构信息

Division of Dermatology, Department of Medicine, University of Massachusetts Medical School, Worcester 01605, USA.

出版信息

Arch Pediatr Adolesc Med. 2005 Jan;159(1):64-7. doi: 10.1001/archpedi.159.1.64.

Abstract

BACKGROUND

Pityrosporum folliculitis is a common inflammatory skin disorder that may mimic acne vulgaris. Some adolescents with recalcitrant follicular pustules or papules may have acne and Pityrosporum folliculitis simultaneously. Clinical response is dependent on treating both conditions.

OBJECTIVES

To demonstrate the similarity in clinical manifestation between acne vulgaris and Pityrosporum folliculitis, the benefit of potassium hydroxide preparation, and the benefit of appropriate antifungal therapy.

PATIENTS

We describe 6 female adolescents with concurrent Pityrosporum folliculitis infection and acne vulgaris.

INTERVENTION

A potassium hydroxide examination was performed on all 6 patients from the exudate of follicular pustules exhibiting spores consistent with yeast. All patients were treated with oral antifungals, and 5 of the 6 patients were also treated with topical antifungals.

RESULTS

Six of 6 patients improved with antifungal treatment. All patients also required some ongoing therapy for their acne.

CONCLUSIONS

These patients demonstrate that follicular papulopustular inflammation of the face, back, and chest may be due to a combination of acne vulgaris and Pityrosporum folliculitis, a common yet less frequently identified disorder. Symptoms often wax and wane depending on the patient's activities, time of the year, current treatment regimens, and other factors. Pityrosporum folliculitis will often worsen with traditional acne therapy and dramatically respond to antifungal therapy.

摘要

背景

马拉色菌毛囊炎是一种常见的炎症性皮肤病,可能类似寻常痤疮。一些患有顽固性毛囊脓疱或丘疹的青少年可能同时患有痤疮和马拉色菌毛囊炎。临床反应取决于对两种病症的治疗。

目的

证明寻常痤疮和马拉色菌毛囊炎在临床表现上的相似性、氢氧化钾制剂的益处以及适当抗真菌治疗的益处。

患者

我们描述了6名同时患有马拉色菌毛囊炎感染和寻常痤疮的女性青少年。

干预

对所有6名患者的毛囊脓疱渗出物进行氢氧化钾检查,发现有与酵母一致的孢子。所有患者均接受口服抗真菌药治疗,6名患者中有5名还接受了外用抗真菌药治疗。

结果

6名患者中有6名经抗真菌治疗后病情改善。所有患者的痤疮也都需要一些持续治疗。

结论

这些患者表明,面部、背部和胸部的毛囊丘疹脓疱性炎症可能是寻常痤疮和马拉色菌毛囊炎共同作用的结果,马拉色菌毛囊炎是一种常见但较少被识别的病症。症状通常会因患者的活动、一年中的时间、当前的治疗方案和其他因素而时好时坏。马拉色菌毛囊炎通常会因传统的痤疮治疗而加重,对抗真菌治疗有显著反应。

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