Komatsu Sei, Hirayama Atsushi, Omori Yosuke, Ueda Yasunori, Mizote Isamu, Fujisawa Yasuo, Kiyomoto Masayoshi, Higashide Toshiaki, Kodama Kazuhisa
Cardiovascular Division, Osaka Police Hospital, Osaka, Japan.
Circ J. 2005 Jan;69(1):72-7. doi: 10.1253/circj.69.72.
Previous reports suggest that plaque may be characterized by the computed tomography (CT) number, but there is not a comprehensive method for evaluating the gray-scale CT image of the coronary artery obtained by multi-detector row CT (MDCT).
Forty-five patients with acute coronary syndrome (ACS) underwent MDCT either 3-4 weeks after the onset of acute myocardial infarction (n=24) or within 1 week after percutaneous coronary intervention in patients with unstable angina (UA; n=21). The cross-sections obtained at intervals of 5 mm were converted to numerical data and a 'plaque map' was drawn using the color-based isometric line method and bird's eye view. 'Plaque map' was compared with the findings of intravascular ultrasound (IVUS) and angioscopy. Of 662 slices of 78 vessels, soft, intermediate or calcified plaque was detected in 144, 134, and 84 slices, respectively. Compared with IVUS, the sensitivities were 92%, 87%, and 89%, respectively, and compared with angioscopy, sensitivity was 80% and specificity was 87%.
MDCT with the 'Plaque Map' system can noninvasively characterize plaque in patients with ACS.
先前的报告表明，斑块可通过计算机断层扫描（CT）值来表征，但尚无一种全面的方法用于评估多排探测器CT（MDCT）获得的冠状动脉灰度CT图像。
45例急性冠状动脉综合征（ACS）患者在急性心肌梗死发病后3 - 4周（n = 24）或不稳定型心绞痛（UA；n = 21）患者经皮冠状动脉介入治疗后1周内接受了MDCT检查。以5毫米间隔获取的横截面被转换为数值数据，并使用基于颜色的等距线法和鸟瞰图绘制“斑块图”。将“斑块图”与血管内超声（IVUS）和血管镜检查结果进行比较。在78条血管的662个切片中，分别在144、134和84个切片中检测到软斑块、中等斑块或钙化斑块。与IVUS相比，敏感性分别为92%、87%和89%，与血管镜检查相比，敏感性为80%，特异性为87%。
采用“斑块图”系统的MDCT能够无创地表征ACS患者的斑块。
