Zatelli M C, Scanarini M, Bondanelli M, Ambrosio M R, degli Uberti E C
Section of Endocrinology, Department of Biomedical Sciences and Advanced Therapies, University of Ferrara, Ferrara, Italy.
J Endocrinol Invest. 2004 Sep;27(8):770-3. doi: 10.1007/BF03347521.
Few cases are reported concerning the association between cerebral aneurysms and acromegaly, and this is the first case report documenting an increase in diameter of a cerebral aneurysm in persistent acromegaly. Persistently elevated GH plasma levels might promote an increase in diameter of cerebral aneurysms. An accurate follow-up in acromegalic patients is important, especially concerning the cerebrovascular system. Establishing the effectiveness and usefulness of this strategy will require future prospective studies.
关于脑动脉瘤与肢端肥大症之间关联的病例报道较少,这是首例记录持续性肢端肥大症患者脑动脉瘤直径增大的病例报告。持续升高的血浆生长激素水平可能促使脑动脉瘤直径增大。对肢端肥大症患者进行准确的随访很重要,尤其是关于脑血管系统。确定该策略的有效性和实用性将需要未来的前瞻性研究。