Beilin Y, Leibowitz A B
The Mount Sinai Medical Center, Department of Anesthesiology, One Gustave L. Levy Place, Box 1010, New York, NY 10029, USA.
Int J Obstet Anesth. 1993;2(2):96-7. doi: 10.1016/0959-289x(93)90087-x.
Achondroplasia is a physeal dysplasia which leads to dwarfism secondary to a decrease in the proliferation of cartilage in the growth plate. This, coupled with normal persistent bone formation, leads to the development of short tubular bones. Achondroplastic dwarfism is among the more common types of dwarfism and is inherited as an autosomal dominant trait. Its incidence is reported as 1 in 26,000 live births. Most achondroplastic dwarfs have a normal life span. The selection and management of anesthesia for the achondroplastic dwarf must take into account a variety of anatomic deformities. The physiologic and hormonal changes of pregnancy further complicate anesthetic administration. We report the safe use of a continuous lumbar epidural anesthetic in an achondroplastic dwarf who presented for urgent cesarean section.
软骨发育不全是一种骨骺发育异常，由于生长板中软骨增殖减少而导致侏儒症。这与持续正常的骨形成相结合，导致短管状骨的发育。软骨发育不全性侏儒症是较为常见的侏儒症类型之一，呈常染色体显性遗传。据报道，其发病率为每26000例活产中有1例。大多数软骨发育不全性侏儒症患者寿命正常。为软骨发育不全性侏儒症患者选择和管理麻醉时，必须考虑到各种解剖畸形。妊娠时的生理和激素变化使麻醉管理更加复杂。我们报告了在一名因紧急剖宫产就诊的软骨发育不全性侏儒症患者中安全使用连续腰段硬膜外麻醉的情况。
