Xu Kaisheng, Shang Xuejun, Chen Yonggang, Zhao Feng, Zhu Peiyuan, Huang Yufeng
Laboratory of Reproduction & Genetics, Nanjing General Hospital of Nanjing Command, PLA, Nanjing, Jiangsu 210002, China.
Zhonghua Nan Ke Xue. 2004 Dec;10(12):900-1, 906.
To measure uric acid of seminal plasma in fertile and infertile males.
One hundred and sixty-three infertile males were divided into an obstructive azoospermic group (15 cases), a non-obstructive azoospermic group (36 cases), an oligozoospermic group (43 cases), and an asthenozoospermic group (69 cases). Twenty fertile males were included in the control group. Uric acid concentrations of seminal plasma in the fertile and infertile men were assessed by spectrophotometer, and sperm parameters were analyzed by computer-assisted semen analysis (CASA) system.
Uric acid concentration of seminal plasma in the control group was significantly higher than all the infertile groups (P < 0.01), and that of the obstructive azoospermic group significantly lower than the other infertile groups (P < 0.1), but no significant difference was observed among the other infertile groups (P > 0.05).
Uric acid may play an important role in male reproduction because of its antioxidative property.
检测生育男性与不育男性精液中的尿酸。
163例不育男性被分为梗阻性无精子症组（15例）、非梗阻性无精子症组（36例）、少精子症组（43例）和弱精子症组（69例）。20例生育男性纳入对照组。采用分光光度计评估生育男性与不育男性精液中尿酸浓度，通过计算机辅助精液分析（CASA）系统分析精子参数。
对照组精液中尿酸浓度显著高于所有不育组（P<0.01），梗阻性无精子症组显著低于其他不育组（P<0.1），但其他不育组间差异无统计学意义（P>0.05）。
尿酸因其抗氧化特性可能在男性生殖中发挥重要作用。
