Hirano Asao
Division of Neuropathology, Department of Pathology, Montefiore Medical Center, Bronx, NY, 10467-2094, USA.
Acta Neuropathol. 2005 Jan;109(1):115-23. doi: 10.1007/s00401-004-0960-x. Epub 2005 Jan 12.
The electron microscope has been an essential instrument for elucidating the morphology of cells and tissue. Fine structural investigation of nervous tissue has disclosed numerous new findings, which were once invisible. In this communication I present my personal perspective on the role of electron microscopy in neuropathology through the presentation of selected electron microscopic projects engaged in our institution. These include brain edema, structural analysis of the myelin in the central nervous system, endodermal cysts in the central nervous system, aberrant synaptic development, toxoplasmosis in AIDS, and Hirano bodies.
电子显微镜一直是阐明细胞和组织形态的重要工具。对神经组织的精细结构研究揭示了许多曾经不可见的新发现。在本报告中，我将通过展示我们机构参与的选定电子显微镜项目，阐述我个人对电子显微镜在神经病理学中作用的看法。这些项目包括脑水肿、中枢神经系统髓鞘的结构分析、中枢神经系统内胚层囊肿、异常突触发育、艾滋病中的弓形虫病以及 Hirano 小体。
