Jensen T S, de Fine Olivarius B, Kraft M, Hansen H J
Department of Neurology, Aarhus Kommunehospital, DK 8000 Aarhus C, Denmark.
Cephalalgia. 1981 Mar;1(1):33-9. doi: 10.1111/j.1468-2982.1981.tb00006.x.
Six patients (two females and four males in one family) with hemiplegic migraine are described. The age of onset was between six and eighteen years. Hemiplegic attacks were usually accompanied by transient neurological disturbances referable to the territory of the vertebrobasilar arterial tree. Brain-stem involvement and vertebrobasilar dysfunction in the reported family was supported by angiography in one case, revealing a marked and prolonged spasm of the basilar artery. Despite its dramatic character and occasionally prolonged deficits the course was essentially benign. Hemiplegic attacks disappeared during adolescence in five of the six patients. No permanent neurological residual phenomena were encountered during a mean follow-up of 14 years. The possibility is raised of a genetically determined susceptibility to periodic vasoconstriction in a particular vascular area as the basis of the syndrome.
本文描述了6例偏瘫性偏头痛患者（来自一个家庭，其中2例女性，4例男性）。发病年龄在6至18岁之间。偏瘫发作通常伴有涉及椎基底动脉系统供血区域的短暂性神经功能障碍。在该报道的家庭中，1例患者经血管造影证实存在脑干受累及椎基底动脉功能障碍，显示基底动脉明显且持久的痉挛。尽管其症状严重且偶尔伴有长期功能缺损，但其病程基本为良性。6例患者中有5例在青春期偏瘫发作消失。在平均14年的随访期间未发现永久性神经功能残留现象。该综合征的发病基础可能是由基因决定的特定血管区域对周期性血管收缩的易感性。
