土耳其儿童中超声确诊的囊性棘球蚴病与血清学阳性之间的差异。
A discrepancy between cystic echinococcosis confirmed by ultrasound and seropositivity in Turkish children.
作者信息
Ozkol Mine, Kilimcioğlu Ali A, Girginkardeşler Nogay, Balcioğlu I Cüneyt, Sakru Nermin, Korkmaz Metin, Ok Ulgen Z
机构信息
Department of Radiology, Faculty of Medicine, Celal Bayar University, 45040-Manisa, Turkey.
出版信息
Acta Trop. 2005 Feb;93(2):213-6. doi: 10.1016/j.actatropica.2004.11.002. Epub 2004 Dec 23.
In three randomly selected villages of Manisa, Turkey, 630 primary school children were examined for cystic echinococcosis (CE) by a portable ultrasound scanner (US) and chest microfilm. Sera samples of 483 (76.7%) children were tested for anti-E. granulosus antibodies by ELISA and indirect hemagglutination (IHA) tests. Hepatic CE were detected in two cases (0.3%) by US, while 43 (8.9%) and 49 (10.1%) cases were found to be positive for CE by ELISA and IHA, respectively. The high seropositivity levels could have been attributed to extra-abdominal or abortive Echinococcus infections, but probably most of them were false-positives. Due to the discrepancy in results, US should be selected as the primary test in field studies and serologic tests should be performed in all cases with suspected lesions. We could not find any reported community based study on CE in Turkey, in which US was applied; but our results suggest that extensive epidemiological studies are required.
在土耳其马尼萨随机挑选的三个村庄中，使用便携式超声扫描仪（US）和胸部缩微胶片对630名小学生进行了囊型包虫病（CE）检查。对483名（76.7%）儿童的血清样本进行了ELISA和间接血凝试验（IHA），以检测抗细粒棘球绦虫抗体。通过超声检查在两例（0.3%）中发现了肝囊型包虫病，而ELISA和IHA检测分别发现43例（8.9%）和49例（10.1%）囊型包虫病呈阳性。高血清阳性率可能归因于腹外或流产型棘球绦虫感染，但其中大多数可能为假阳性。由于结果存在差异，在现场研究中应选择超声检查作为主要检测方法，对所有疑似病变病例都应进行血清学检测。我们未找到土耳其有任何应用超声检查的关于囊型包虫病的社区研究报道；但我们的结果表明需要进行广泛的流行病学研究。
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