A structure-taste study of arylsulfonyl(cyclo)alkanecarboxylic acids.
作者信息
Lysiak Violetta, Ratajczak Aleksander, Mencel Agnieszka, Jarzembek Krystyna, Polanski Jaroslaw
机构信息
Department of Organic Chemistry, Institute of Chemistry, University of Silesia, PL-40-006 Katowice, Poland.
出版信息
Bioorg Med Chem. 2005 Feb 1;13(3):671-5. doi: 10.1016/j.bmc.2004.10.056.
PMID:15653334
Abstract
A number of sweeteners contain a sulfonyl group. In our current search for new glucophores several new compounds containing such group were obtained. A series of novel 1-phenylsulfonylcyklohexanecarboxylic acids and 2-arylsulfonylalkanecarboxylic acids was obtained and evaluated for their sweet taste quality. It has been found that methyl substituents are of the key importance for the activity of these compounds.
摘要
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