Scialpi M, Midiri M, Bartolotta T V, Cazzolla M P, Rotondo A, Resta M C, Lagalla R, Cardinale A E
Department of Radiology, Santissima Annunziata Hospital, Taranto, Italy.
Abdom Imaging. 2005 Mar-Apr;30(2):222-7. doi: 10.1007/s00261-004-0229-9. Epub 2005 Dec 30.
We assessed the potential usefulness of contrast-enhanced power Doppler ultrasonography (US) for differentiating pancreatic carcinoma from chronic focal pancreatitis.
Twenty-six consecutive patients with ductal carcinoma (n=16) and chronic focal pancreatitis (n=10) underwent power Doppler US examinations before and after intravenous injection of an air-based contrast agent (Levovist, Schering, Berlin, Germany). Final diagnosis was obtained by surgery in all patients. The following parameters before and after intravenous administration of contrast agent were evaluated for each lesion: number, morphology and course of the vessels within the lesion and time to maximum detectable enhancement. Number of the lesion vessels and time to maximum enhancement for each lesion were compared by with Student t test.
After injection of contrast agent, nine of 16 (56.2%) carcinomas showed a larger total number of vessels (p<0.005) and faster enhancement (p<0.0001) compared with chronic focal pancreatitis. Irregular vessels with a serpiginous course that penetrated the tumor was predominant in carcinoma (eight of 16 cases), whereas focal pancreatitis presented mostly as avascular masses (five of 10 cases).
Contrast-enhanced power Doppler US provides useful findings for differentiating pancreatic carcinoma from chronic focal pancreatitis.
我们评估了超声造影能量多普勒超声检查（US）在鉴别胰腺癌与慢性局灶性胰腺炎方面的潜在应用价值。
26例连续性患者，其中导管癌患者16例，慢性局灶性胰腺炎患者10例，在静脉注射基于空气的造影剂（德国柏林先灵公司生产的Levovist）前后接受了能量多普勒超声检查。所有患者均通过手术获得最终诊断。对每个病变在静脉注射造影剂前后的以下参数进行评估：病变内血管的数量、形态和走行以及最大可检测增强时间。通过Student t检验比较每个病变的血管数量和最大增强时间。
注射造影剂后，与慢性局灶性胰腺炎相比，16例（56.2%）癌中的9例显示血管总数更多（p<0.005）且增强更快（p<0.0001）。癌中以不规则、呈匐行状走行且穿透肿瘤的血管为主（16例中有8例），而局灶性胰腺炎大多表现为无血管肿块（10例中有5例）。
超声造影能量多普勒超声为鉴别胰腺癌与慢性局灶性胰腺炎提供了有用的发现。
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