Román-Sánchez P, Conthe P, García-Alegría J, Forteza-Rey J, Montero M, Montoto C
Hospital General de Requena, Paraje Casablanca s/n, 46340 Valencia, Spain.
QJM. 2005 Feb;98(2):127-38. doi: 10.1093/qjmed/hci019. Epub 2005 Jan 17.
The medical management of heart failure (HF) in clinical practice varies considerably by country and by medical specialty.
To assess the treatment of HF patients admitted to Internal Medicine departments, and to evaluate out-patient management prior to admission, by specialty.
Prospective cross-sectional multi-centre survey.
Of 55 randomly selected Spanish hospitals, 51 agreed to participate. All patients (n = 2145) consecutively admitted for decompensated HF to the Departments of Internal Medicine of these hospitals, over 5 months, were included. Twenty variables were analysed, including aspects relating to out-patient management prior to admission.
Mean +/- SD age was 77.2 +/- 10.5 years, 57.3% were female, 47% had systolic dysfunction. Prescriptions at discharge: loop diuretics 85.6%, spironolactone 29.8%, ACEIs 65.8%, beta-blockers 8.7%, cardiac glycosides 39%. At admission, 86% already had a diagnosis of HF. Of these, 53% (older patients and more women) were being treated on an out-patient basis by primary care physicians. Primary care physicians requested fewer echocardiograms than internists (38% vs. 69%, p<0.001) and prescribed fewer drugs (ACEIs 40% vs. 54%, p<0.001; spironolactone 15% vs. 23%, p<0.05; beta-blockers 6% vs. 13%, p<0.01). The internists treated more incapacitated patients than the cardiologists (p<0.001), prescribed more high-dose ACEIs (20% vs. 13%, p<0.01) and spironolactone (26% vs. 20%, p<0.05), and fewer anticoagulants (32% vs. 39%, p<0.05).
Patients admitted to medical departments with HF are different to those found in clinical trials. Their management is currently suboptimal. Differences in treatment between internists and cardiologists appear to be accounted for by differences in the patients they treat.
在临床实践中,心力衰竭(HF)的药物治疗在不同国家和医学专科之间存在很大差异。
评估内科收治的HF患者的治疗情况,并按专科评估入院前的门诊管理情况。
前瞻性横断面多中心调查。
在随机选择的55家西班牙医院中,有51家同意参与。纳入了在5个月内连续入住这些医院内科、因失代偿性HF入院的所有患者(n = 2145)。分析了20个变量,包括与入院前门诊管理相关的方面。
平均±标准差年龄为77.2±10.5岁,57.3%为女性,47%有收缩功能障碍。出院时的处方:袢利尿剂85.6%,螺内酯29.8%,ACEI类药物65.8%,β受体阻滞剂8.7%,强心苷39%。入院时,86%的患者已被诊断为HF。其中,53%(老年患者和更多女性)由初级保健医生进行门诊治疗。初级保健医生要求进行超声心动图检查的比例低于内科医生(38%对69%,p<0.001),且开具的药物较少(ACEI类药物40%对54%,p<0.001;螺内酯15%对23%,p<0.05;β受体阻滞剂6%对13%,p<0.01)。内科医生治疗的失能患者比心脏病专家更多(p<0.001),开具的高剂量ACEI类药物(20%对13%,p<0.01)和螺内酯(26%对20%,p<0.05)更多,而开具抗凝剂的比例更低(32%对39%,p<0.05)。
因HF入住内科的患者与临床试验中的患者不同。他们目前的管理并不理想。内科医生和心脏病专家在治疗上的差异似乎是由他们所治疗患者的差异所导致的。