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本文引用的文献

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Time-dependent bias was common in survival analyses published in leading clinical journals.时间依赖性偏倚在主要临床杂志发表的生存分析中很常见。
J Clin Epidemiol. 2004 Jul;57(7):672-82. doi: 10.1016/j.jclinepi.2003.12.008.
2
Impact of sex on long-term mortality from acute myocardial infarction vs unstable angina.性别对急性心肌梗死与不稳定型心绞痛长期死亡率的影响。
Arch Intern Med. 2003 Nov 10;163(20):2476-84. doi: 10.1001/archinte.163.20.2476.
3
Care and outcomes of patients newly hospitalized for heart failure in the community treated by cardiologists compared with other specialists.与其他专科医生相比,心脏病专家治疗的社区中新住院心力衰竭患者的护理及治疗结果。
Circulation. 2003 Jul 15;108(2):184-91. doi: 10.1161/01.CIR.0000080290.39027.48. Epub 2003 Jun 23.
4
Is specialty care associated with improved survival of patients with congestive heart failure?
Am Heart J. 2003 Feb;145(2):300-9. doi: 10.1067/mhj.2003.54.
5
Cardiology participation improves outcomes in patients with new-onset heart failure in the outpatient setting.心脏病学专家的参与可改善门诊环境下新发心力衰竭患者的治疗效果。
J Am Coll Cardiol. 2003 Jan 1;41(1):62-8. doi: 10.1016/s0735-1097(02)02493-2.
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The underutilization of cardiac medications of proven benefit, 1990 to 2002.1990年至2002年,已证实有益的心脏药物未得到充分利用。
J Am Coll Cardiol. 2003 Jan 1;41(1):56-61. doi: 10.1016/s0735-1097(02)02670-0.
7
Burden of systolic and diastolic ventricular dysfunction in the community: appreciating the scope of the heart failure epidemic.社区中收缩期和舒张期心室功能障碍的负担:认识心力衰竭流行的范围。
JAMA. 2003 Jan 8;289(2):194-202. doi: 10.1001/jama.289.2.194.
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The effects of beta-blockers on morbidity and mortality in a population-based cohort of 11,942 elderly patients with heart failure.β受体阻滞剂对11942例老年心力衰竭患者人群发病率和死亡率的影响。
Am J Med. 2002 Dec 1;113(8):650-6. doi: 10.1016/s0002-9343(02)01346-3.
9
Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey.基层医疗中心力衰竭的管理(心力衰竭改善计划):一项国际调查。
Lancet. 2002 Nov 23;360(9346):1631-9. doi: 10.1016/s0140-6736(02)11601-1.
10
A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario.安大略省心脏监护病房收治患者的医院出院管理数据编码准确性的多中心研究。
Am Heart J. 2002 Aug;144(2):290-6. doi: 10.1067/mhj.2002.123839.

专科随访对充血性心力衰竭门诊患者的影响。

Impact of specialist follow-up in outpatients with congestive heart failure.

作者信息

Ezekowitz Justin A, van Walraven Carl, McAlister Finlay A, Armstrong Paul W, Kaul Padma

机构信息

Division of Cardiology, University of Alberta, Edmonton, Alta.

出版信息

CMAJ. 2005 Jan 18;172(2):189-94. doi: 10.1503/cmaj.1032017.

DOI:10.1503/cmaj.1032017
PMID:15655239
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC543981/
Abstract

BACKGROUND

There is uncertainty about whether physician specialty influences the outcomes of outpatients with congestive heart failure after adjustment for differences in case mix. Our objective was to determine the impact of physician specialty on outcomes in outpatients with new-onset congestive heart failure.

METHODS

The study was a population-based retrospective cohort study involving patients with new-onset congestive heart failure discharged from 128 acute care hospitals in Alberta between Apr. 1, 1998, and July 1, 2000. Outcomes were resource utilization (clinic visits, emergency department visits and hospital admissions) and survival at 30 days and 1 year.

RESULTS

A total of 3136 patients were discharged from hospital with a new diagnosis of congestive heart failure (median age 76 years, 50% men). Of these, 1062 (34%) received no follow-up visits for cardiovascular care, 738 (24%) were seen by a family physician (FP) alone, 29 (1%) by a specialist (cardiologist or general internist) alone and 1307 (42%) by both a specialist and an FP. Compared with patients who received no follow-up cardiovascular care, patients who received regular cardiovascular follow-up visits with a physician had fewer visits to the emergency department (38% v. 80%), fewer were admitted to hospital (13% v. 94%), and the adjusted 1-year mortality was lower (22% v. 37%) (all p < 0.001). Compared with patients who received combined specialist and FP care, patients cared for exclusively by FPs had fewer outpatient visits (median 9 v. 17 in the first year), fewer of these patients presented to the emergency department (24% v. 45% in the first year), and fewer were readmitted for cardiovascular care (7% v. 16%) (all p < 0.001). However, the adjusted mortality at 1 year was lower among patients treated with combined care (17% v. 28%, p < 0.001) despite a higher burden of comorbidities. In a multivariate model adjusting for comorbidities (with no cardiovascular follow-up visits as the reference category), the mortality was lower among patients followed on an outpatient basis by an FP alone (odds ratio [OR] 0.66, 95% confidence interval [CI] 0.53-0.82) or by an FP and a specialist (OR 0.34, 95% CI 0.28-0.42). In a proportional hazards model with time-dependent covariates (with adjustment for frequency of follow-up visits), the risk of all-cause mortality was reduced significantly (hazard ratio 0.98, 95% CI 0.97- 0.99) with each specialist visit compared with FP care alone.

INTERPRETATION

Patients with congestive heart failure followed by both specialists and FPs had significantly better survival than those followed by FPs alone (or those who received no specific cardiovascular follow-up care). Methods to improve timely and appropriate access to specialists and to improve collaborative care structures are needed.

摘要

背景

在对病例组合差异进行调整后,医师专业是否会影响充血性心力衰竭门诊患者的治疗结果尚不确定。我们的目的是确定医师专业对新发充血性心力衰竭门诊患者治疗结果的影响。

方法

该研究是一项基于人群的回顾性队列研究,涉及1998年4月1日至2000年7月1日期间从艾伯塔省128家急症医院出院的新发充血性心力衰竭患者。治疗结果包括资源利用情况(门诊就诊、急诊科就诊和住院情况)以及30天和1年时的生存率。

结果

共有3136例患者因新发充血性心力衰竭出院(中位年龄76岁,50%为男性)。其中,1062例(34%)未接受心血管护理随访,738例(24%)仅由家庭医生诊治,29例(1%)仅由专科医生(心脏病专家或普通内科医生)诊治,1307例(42%)由专科医生和家庭医生共同诊治。与未接受心血管护理随访的患者相比,接受医生定期心血管随访的患者急诊科就诊次数更少(38%对80%),住院人数更少(13%对94%),调整后的1年死亡率更低(22%对37%)(所有p<0.001)。与接受专科医生和家庭医生联合治疗的患者相比,仅由家庭医生治疗的患者门诊就诊次数更少(第一年中位就诊次数为9次对17次),这些患者中到急诊科就诊的人数更少(第一年为24%对45%),因心血管护理再次住院的人数更少(7%对16%)(所有p<0.001)。然而,尽管合并症负担较高,但联合治疗患者的1年调整死亡率较低(17%对28%,p<0.001)。在一个调整了合并症的多变量模型中(以未进行心血管随访为参考类别),仅由家庭医生进行门诊随访的患者死亡率较低(比值比[OR]0.66,95%置信区间[CI]0.53 - 0.82),由家庭医生和专科医生进行门诊随访的患者死亡率更低(OR 0.34,95%CI 0.28 - 0.42)。在一个具有时间依赖性协变量的比例风险模型中(对随访就诊频率进行调整),与仅由家庭医生治疗相比,每次专科医生就诊可显著降低全因死亡风险(风险比0.98,95%CI 0.97 - 0.99)。

解读

由专科医生和家庭医生共同随访的充血性心力衰竭患者的生存率显著高于仅由家庭医生随访的患者(或未接受特定心血管随访护理的患者)。需要采取措施改善及时、适当获得专科医生服务的机会,并改善协作护理结构。