Katenkamp K, Henke R-P, Katenkamp D
Institut für Pathologie, Klinikum der Friedrich-Schiller-Universität Jena.
Pathologe. 2005 Mar;26(2):149-52. doi: 10.1007/s00292-004-0744-z.
This case describes the history of disease of a 53-year old man, who has been treated for a putative recurrent nailbed granuloma of the right big toe since 1996. In 2000 an enlarged inguinal lymph node was excised. The light microscopic examination showed a metastasis of a malignant melanoma. In 2003 we received a tumor of the right big toe for histopathological examination. The histological and immunohistochemical results proved a dermal chondroid melanoma. This extremely rare variant of malignant melanoma occurs particularly in subungual location and is possibly related to a previous trauma. We discuss the spectrum of differential diagnoses and the importance of immunohistochemistry.