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婴儿期脑桥外髓鞘溶解症:一例报告

Extrapontine myelinolysis in infancy: report of a case.

作者信息

Haspolat Senay, Duman Ozgur, Senol Utku, Yegin Olcay

机构信息

Department of Pediatric Neurology, Akdeniz University, Medical School, Antalya, Turkey.

出版信息

J Child Neurol. 2004 Nov;19(11):913-5.

Abstract

Osmotic myelinolysis is a rare, acute, demyelinating process that involves the pons (central pontine myelinolysis) and other locations of the central nervous system (extrapontine myelinolysis). Central pontine myelinolysis is described in children, usually associated with rapid correction of hyponatremia. Other conditions, such as hypernatremia and hyperglycemia, have also been reported as being responsible for pontine myelinolysis. Extrapontine myelinolysis in childhood is very rare and presents in a wide variety of locations. We report a patient who developed extrapontine myelinolysis in the cerebellum during treatment of hyponatremic dehydration. This is the first case reported during infancy.

摘要

渗透性脱髓鞘是一种罕见的急性脱髓鞘过程,累及脑桥(中枢性脑桥脱髓鞘)和中枢神经系统的其他部位(脑桥外脱髓鞘)。中枢性脑桥脱髓鞘在儿童中较为常见,通常与低钠血症的快速纠正有关。其他情况,如高钠血症和高血糖,也被报道可导致脑桥脱髓鞘。儿童期脑桥外脱髓鞘非常罕见,可出现在多种部位。我们报告了1例在低钠性脱水治疗期间发生小脑脑桥外脱髓鞘的患者。这是婴儿期报道的首例病例。

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