Doyle Mark R, Bizzell Colleen M, Keller Melissa R, Michaels Scott D, Song Judong, Noh Yoo-Sun, Amasino Richard M
Department of Biochemistry, College of Agricultural and Life Sciences, University of Wisconsin, Madison, WI 53706-1544, USA.
Plant J. 2005 Feb;41(3):376-85. doi: 10.1111/j.1365-313X.2004.02300.x.
The HUA2 gene acts as a repressor of floral transition. Lesions in hua2 were identified through a study of natural variation and through two mutant screens. An allele of HUA2 from Landsberg erecta (Ler) contains a premature stop codon and acts as an enhancer of early flowering 4 (elf4) mutants. hua2 single mutants, in the absence of the elf4 lesion, flower earlier than wild type under short days. hua2 mutations partially suppress late flowering in FRIGIDA (FRI )-containing lines, autonomous pathway mutants, and a photoperiod pathway mutant. hua2 mutations suppress late flowering by reducing the expression of several MADS genes that act as floral repressors including FLOWERING LOCUS C (FLC ) and FLOWERING LOCUS M (FLM ).
HUA2基因作为开花转变的抑制因子。通过对自然变异的研究以及两次突变筛选鉴定出了hua2中的损伤。来自直立型拟南芥(Ler)的HUA2等位基因含有一个提前的终止密码子,并作为早花4(elf4)突变体的增强子。在没有elf4损伤的情况下,hua2单突变体在短日照条件下比野生型开花更早。hua2突变部分抑制了含有FRIGIDA(FRI)的株系、自主途径突变体和光周期途径突变体中的晚花现象。hua2突变通过降低几个作为开花抑制因子的MADS基因的表达来抑制晚花,这些基因包括开花位点C(FLC)和开花位点M(FLM)。