腹腔镜供肾切除术与开放性活体供肾切除术：一项生活质量与功能研究。

Laparoscopic donor nephrectomy vs. open live donor nephrectomy: a quality of life and functional study.

作者信息

Buell Joseph F, Lee Lucy, Martin Jill E, Dake Natalie A, Cavanaugh Teresa M, Hanaway Michael J, Weiskittel Pat, Munda Rino, Alexander J Wesley, Cardi Michael, Peddi V Ram, Zavala Edward Y, Berilla Elaine, Clippard Marketa, First M Roy, Woodle E Steve

机构信息

The University Hospital, Cincinnati, OH 45267-0004, USA.

出版信息

Clin Transplant. 2005 Feb;19(1):102-9. doi: 10.1111/j.1399-0012.2004.00308.x.

DOI:10.1111/j.1399-0012.2004.00308.x

PMID:15659142

Abstract

BACKGROUND

Few studies have compared the quality of life (QoL) and functional recuperation of laproscopic donor nephrectomy (LDN) vs. open donor nephrectomy (ODN) donors. This study utilized the SF-36 health survey, single-item health-related quality of life (HRQOL) score, and a functional assessment questionnaire ('Donor Survey').

METHODS

Questionnaires were sent to 100 LDN and 50 ODN donors. These donors were patients whose procedures were performed at The University Hospital and The Christ Hospital in Cincinnati, Ohio.

RESULTS

A total of 46 (46%) LDN and 21 (42%) ODN donors returned the completed surveys. The demographics of the two groups were similar. LDN patients reported a more rapid return to 100% normal health (69 vs. 116 d; p = 0.24), part-time work (21.9 vs. 23.2 d; p = 0.09), and necessitated fewer physician office visits post-operative (2.8 vs. 4.4; p = 0.01). ODN patients reported shorter duration of oral pain medication use (13.4 vs. 7.2 d; p = 0.02). However, a greater number of ODN patients reported post-surgical chronic pain (3 vs. 6; p < 0.05) and hernia (0 vs. 2; p = 0.19). The overall QoL for both groups was comparable with the general USA population.

CONCLUSIONS

The results of this study support the decisions of many kidney transplant centers to adopt LDN programs as standard of care.

摘要

背景

很少有研究比较腹腔镜供肾切除术（LDN）与开放性供肾切除术（ODN）供者的生活质量（QoL）和功能恢复情况。本研究采用了SF-36健康调查、单项目健康相关生活质量（HRQOL）评分以及一份功能评估问卷（“供者调查问卷”）。

方法

向100例LDN供者和50例ODN供者发放问卷。这些供者是在俄亥俄州辛辛那提市大学医院和基督医院接受手术的患者。

结果

共有46例（46%）LDN供者和21例（42%）ODN供者返回了完整的调查问卷。两组的人口统计学特征相似。LDN患者报告恢复到100%正常健康状态的时间更快（69天对116天；p = 0.24），恢复兼职工作的时间更快（21.9天对23.2天；p = 0.09），术后看医生的次数更少（2.8次对4.4次；p = 0.01）。ODN患者报告口服止痛药物使用的持续时间更短（13.4天对7.2天；p = 0.02）。然而，更多的ODN患者报告有术后慢性疼痛（3例对6例；p < 0.05）和疝气（0例对2例；p = 0.19）。两组的总体生活质量与美国普通人群相当。