Voskoboinik A, Gutman M J, Croagh D, Bell R, Saunder A, Gribbin J, Kanellis J
Department of General Surgery, Monash Medical Centre, Clayton, Australia.
Asian J Endosc Surg. 2011 Aug;4(3):127-32. doi: 10.1111/j.1758-5910.2011.00092.x. Epub 2011 Jun 20.
Traditionally performed by vascular surgeons or urologists, laparoscopic nephrectomy for live kidney donor transplantation has emerged as a new effective and safe technique. This study examines the implementation of this technique at our centre, as performed by a single general surgeon with expertise in advanced laparoscopic surgery.
Patient records for 78 live donor transplants performed between February 2002 and September 2008 were divided into two groups (with 39 patients each) analyzed. A variety of outcome variables were compared. The same individual surgeon performed all laparoscopic donor nephrectomy (LDN) procedures.
A significant advantage was noted for LDN with respect to hospital stay (LDN 5.1 ± 1.1 days vs open donor nephrectomy [ODN] 6.4 ± 2.6 days, P=0.01) while ODN had a significant advantage with respect to operative time (LDN 241.1 ± 55.7 min vs ODN 152.0 ± 27.7 min, P<0.01). Within the LDN group, we noted a significant shortening in the operation time with each case as experience increased (see graph; P<0.01). The total postoperative complication rate was similar in both groups (LDN: 31% vs ODN: 44%, P=0.25). There was a trend towards more respiratory complications in ODN (ODN 11/39 [28%] vs LDN 5/39 [13%], P=0.09).
While implementing a new procedure may result in longer operative times initially, these improve with time, and our data demonstrates no compromise in patient safety or outcomes. The LDN procedure proved to be a desirable alternative to ODN, with shorter hospital stay and improved operator skills with each case, and without significant compromise in allograft recovery.
活体肾移植的腹腔镜肾切除术传统上由血管外科医生或泌尿外科医生实施,现已成为一种新的有效且安全的技术。本研究探讨了由一位擅长高级腹腔镜手术的普通外科医生在我们中心实施该技术的情况。
将2002年2月至2008年9月期间进行的78例活体供体移植患者记录分为两组(每组39例)进行分析。比较了各种结果变量。所有腹腔镜供体肾切除术(LDN)手术均由同一位外科医生实施。
LDN在住院时间方面具有显著优势(LDN为5.1±1.1天,开放性供体肾切除术[ODN]为6.4±2.6天,P=0.01),而ODN在手术时间方面具有显著优势(LDN为241.1±55.7分钟,ODN为152.0±27.7分钟,P<0.01)。在LDN组中,随着经验的增加,每例手术时间显著缩短(见图;P<0.01)。两组术后总并发症发生率相似(LDN:31%,ODN:44%,P=0.25)。ODN发生呼吸并发症的趋势更明显(ODN为11/39[28%],LDN为5/39[13%],P=0.09)。
虽然实施新手术最初可能会导致手术时间延长,但随着时间推移会有所改善,我们的数据表明患者安全性或结果并未受到影响。LDN手术被证明是ODN的理想替代方案,住院时间更短,且随着每例手术操作技能不断提高,同种异体肾恢复情况也未受到显著影响。