Neurath M, Stofft E
Anatomisches Institut, Johannes-Gutenberg Universität Mainz.
Unfallchirurg. 1992 Jan;95(1):17-20.
The present study concerned 16 human menisci: light, transmission (TEM) and scanning electron microscopic (SEM) techniques were used in addition to histochemical examinations, to define the microstructure of their collagenous fibre systems. A characteristic arrangement of the fibrils was noted. The diameters of the collagen fibrils ranged between 20 and 190 nm in the medial meniscus, the mean value being 67.5 nm (lateral: 70 nm). Many collagen type VI fibrils were detected, and collagen type IV was present. Such an organization has implications for knee joint stability, the variability of the fibril diameters and the characteristic arrangement giving the tissue great tensile stiffness and allows adaptation to all physiological loading conditions. On the surface of the menisci openings of canal-like structures were noted. Their characteristic distribution indicates that they carry nutrients from the synovial fluid to the normal avascular areas of the menisci.
本研究涉及16个人类半月板:除组织化学检查外,还使用了光学、透射电子显微镜(TEM)和扫描电子显微镜(SEM)技术,以确定其胶原纤维系统的微观结构。观察到原纤维的特征性排列。内侧半月板中胶原原纤维的直径在20至190纳米之间,平均值为67.5纳米(外侧:70纳米)。检测到许多VI型胶原原纤维,并且存在IV型胶原。这种组织结构对膝关节稳定性具有影响,原纤维直径的变异性以及特征性排列赋予组织很大的拉伸刚度,并使其能够适应所有生理负荷条件。在半月板表面注意到管状结构的开口。它们的特征性分布表明它们将营养物质从滑液输送到半月板的正常无血管区域。