颅内出血作为重型乙型血友病的首发表现：病例报告及梅奥诊所综合血友病中心经验回顾

Intracranial haemorrhage as initial presentation of severe haemophilia B: case report and review of Mayo Clinic Comprehensive Hemophilia Center experience.

作者信息

Rodriguez V, Schmidt K A, Slaby J A, Pruthi R K

机构信息

Division of Pediatric Hematology/Oncology, Mayo Clinic, Rochester, MN, USA.

出版信息

Haemophilia. 2005 Jan;11(1):73-7. doi: 10.1111/j.1365-2516.2005.01062.x.

DOI:10.1111/j.1365-2516.2005.01062.x

PMID:15660992

Abstract

A neonate who had intracranial haemorrhage (ICH) at birth received a diagnosis of severe haemophilia B at 6 months of age. ICH had been the initial presentation of his bleeding disorder. His family history was negative for haemophilia. Review of our institutional experience as well as the literature indicates that intracranial bleeding as the initial presentation of haemophilia is rare.

摘要

一名出生时患有颅内出血（ICH）的新生儿在6个月大时被诊断为重度乙型血友病。颅内出血是其出血性疾病的最初表现。他的家族史中血友病呈阴性。回顾我们机构的经验以及文献表明，以颅内出血作为血友病的最初表现是罕见的。