Asbury Charles L
Department of Physiology and Biophysics, University of Washington School of Medicine, Seattle, Washington 98195-7290, USA.
Curr Opin Cell Biol. 2005 Feb;17(1):89-97. doi: 10.1016/j.ceb.2004.12.002.
Kinesin, an essential motor protein that moves intracellular cargo along microtubules, walks like a person. When we walk, our feet exchange roles with each step, one moving and one remaining stationary. The moving foot travels twice as far as our torso during a single step, and our body alternates between two configurations (left vs. right leg leading). Recent work shows that kinesin shares all three of these hallmarks of bipedal walking. The challenge now is to determine how the gait of this lilliputian biped is coordinated.
驱动蛋白是一种重要的运动蛋白,它沿着微管移动细胞内的货物,其移动方式像人行走一样。我们行走时,双脚每走一步就交换角色,一只脚移动,另一只脚保持静止。在单一步伐中,移动的脚所移动的距离是我们躯干移动距离的两倍,而且我们的身体在两种形态(左腿在前与右腿在前)之间交替。最近的研究表明,驱动蛋白具备双足行走的所有这三个特征。现在面临的挑战是确定这种微小双足动物的步态是如何协调的。