小鼠脑发育过程中足突细胞粘附分子基因的表达模式
Pattern of expression of the podocalyxin gene in the mouse brain during development.
作者信息
Vitureira Nathalia, McNagny Kelly, Soriano Eduardo, Burgaya Ferran
机构信息
IRBB/PCB, Barcelona Science Park and Department of Cell Biology, University of Barcelona, Josep Samitier 1-5, Barcelona E-08028, Spain.
出版信息
Gene Expr Patterns. 2005 Feb;5(3):349-54. doi: 10.1016/j.modgep.2004.10.002.
We studied the expression pattern of the major renal protein Podocalyxin during the development of mouse brain using in situ hybridization. Podocalyxin mRNA was widely expressed at least from E14, the first age we studied, and expression remained high until adulthood. The highest levels of expression were postnatal. Podocalyxin expression was particularly elevated in the cortical plate, the hippocampus and cerebellum, and in several basal forebrain nuclei.
我们使用原位杂交技术研究了小鼠大脑发育过程中主要肾脏蛋白Podocalyxin的表达模式。至少从我们研究的最早年龄即胚胎第14天开始，Podocalyxin mRNA就广泛表达，并且其表达在成年前一直保持高水平。最高表达水平出现在出生后。Podocalyxin在皮质板、海马体、小脑以及几个基底前脑核中表达特别升高。
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