Azoulay Elie, Pochard Frédéric, Kentish-Barnes Nancy, Chevret Sylvie, Aboab Jérôme, Adrie Christophe, Annane Djilali, Bleichner Gérard, Bollaert Pierre Edouard, Darmon Michael, Fassier Thomas, Galliot Richard, Garrouste-Orgeas Maité, Goulenok Cyril, Goldgran-Toledano Dany, Hayon Jan, Jourdain Mercé, Kaidomar Michel, Laplace Christian, Larché Jérôme, Liotier Jérôme, Papazian Laurent, Poisson Catherine, Reignier Jean, Saidi Fayçal, Schlemmer Benoît
Service de Réanimation Médicale, Hôpital Saint-Louis, Paris, France.
Am J Respir Crit Care Med. 2005 May 1;171(9):987-94. doi: 10.1164/rccm.200409-1295OC. Epub 2005 Jan 21.
Intensive care unit (ICU) admission of a relative is a stressful event that may cause symptoms of post-traumatic stress disorder (PTSD).
Factors associated with these symptoms need to be identified.
For patients admitted to 21 ICUs between March and November 2003, we studied the family member with the main potential decision-making role.
Ninety days after ICU discharge or death, family members completed the Impact of Event Scale (which evaluates the severity of post-traumatic stress reactions), Hospital Anxiety and Depression Scale, and 36-item Short-Form General Health Survey during a telephone interview. Linear regression was used to identify factors associated with the risk of post-traumatic stress symptoms.
Interviews were obtained for family members of 284 (62%) of the 459 eligible patients. Post-traumatic stress symptoms consistent with a moderate to major risk of PTSD were found in 94 (33.1%) family members. Higher rates were noted among family members who felt information was incomplete in the ICU (48.4%), who shared in decision making (47.8%), whose relative died in the ICU (50%), whose relative died after end-of-life decisions (60%), and who shared in end-of-life decisions (81.8%). Severe post-traumatic stress reaction was associated with increased rates of anxiety and depression and decreased quality of life.
Post-traumatic stress reaction consistent with a high risk of PTSD is common in family members of ICU patients and is the rule among those who share in end-of-life decisions. Research is needed to investigate PTSD rates and to devise preventive and early-detection strategies.
亲属入住重症监护病房(ICU)是一件压力巨大的事情,可能会引发创伤后应激障碍(PTSD)的症状。
需要确定与这些症状相关的因素。
对于2003年3月至11月间入住21个ICU的患者,我们研究了具有主要潜在决策作用的家庭成员。
在ICU出院或患者死亡90天后,家庭成员在电话访谈中完成事件影响量表(评估创伤后应激反应的严重程度)、医院焦虑抑郁量表以及36项简短形式一般健康调查问卷。采用线性回归来确定与创伤后应激症状风险相关的因素。
在459名符合条件的患者中,有284名(62%)患者的家庭成员接受了访谈。94名(33.1%)家庭成员存在与PTSD中度至重度风险相符的创伤后应激症状。在那些觉得ICU信息不完整的家庭成员中(48.4%)、参与决策的家庭成员中(47.8%)、亲属在ICU死亡的家庭成员中(50%)、亲属在临终决策后死亡的家庭成员中(60%)以及参与临终决策的家庭成员中(81.8%),创伤后应激症状的发生率更高。严重的创伤后应激反应与焦虑和抑郁发生率增加以及生活质量下降有关。
与PTSD高风险相符的创伤后应激反应在ICU患者的家庭成员中很常见,在参与临终决策的家庭成员中更是如此。需要开展研究以调查PTSD发生率,并制定预防和早期检测策略。