Bi Xiaoming, Li Debiao
Department of Radiology, Northwestern University, Chicago, Illinois, USA.
J Magn Reson Imaging. 2005 Feb;21(2):133-9. doi: 10.1002/jmri.20250.
To evaluate the efficacy of contrast-enhanced coronary magnetic resonance angiography (MRA) at 3.0 T.
Nine healthy human volunteers were studied on a 3.0-T whole-body MR system. A three-dimensional, breathhold, magnetization-prepared, segmented, gradient-echo sequence was used, with injection of 20 mL gadopentetate dimeglumine for each three-dimensional slab. Imaging parameters were optimized based on computer simulations. Signal-to-noise ratio (SNR), contrast-to-noise ratio (CNR), depicted coronary artery length, lumen diameter, and imaging sharpness with contrast agent were evaluated. SNR and CNR were compared to the results from a previous 1.5-T study.
A 53% increment in SNR and a 305% enhancement in CNR were measured with contrast. Vessel length and sharpness depicted were higher and the lumen diameter was lower (all P values < 0.05) in postcontrast images. Compared to previous results from 1.5-T, the SNR, CNR, and vessel sharpness were enhanced at 3.0 T with higher spatial resolution.
Contrast-enhanced, three-dimensional, coronary MRA at 3.0 T is a promising technique for diagnosing coronary artery diseases. Patient studies are necessary to evaluate its clinical utility.
评估3.0 T对比增强冠状动脉磁共振血管造影（MRA）的有效性。
对9名健康志愿者在3.0 T全身MR系统上进行研究。使用三维屏气磁化准备分段梯度回波序列，每个三维层面注射20 mL钆喷酸葡胺。基于计算机模拟优化成像参数。评估信噪比（SNR）、对比噪声比（CNR）、显示的冠状动脉长度、管腔直径以及使用对比剂时的成像清晰度。将SNR和CNR与之前一项1.5 T研究的结果进行比较。
使用对比剂时，SNR增加了53%，CNR提高了305%。对比剂增强后的图像中，显示的血管长度和清晰度更高，管腔直径更小（所有P值<0.05）。与之前1.5 T的结果相比，3.0 T时SNR、CNR和血管清晰度均有所提高，且具有更高的空间分辨率。
3.0 T对比增强三维冠状动脉MRA是诊断冠状动脉疾病的一项有前景的技术。需要进行患者研究以评估其临床实用性。
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