量子传递：不仅适用于神经元。

Quantal transmission: not just for neurons.

作者信息

Overstreet Linda S

机构信息

Vollum Institute, L474, Oregon Health & Sciences University, 3181 SW Sam Jackson Park Road, Portland, OR 97239, USA.

出版信息

Trends Neurosci. 2005 Feb;28(2):59-62. doi: 10.1016/j.tins.2004.11.010.

DOI:10.1016/j.tins.2004.11.010

PMID:15667925

Abstract

Glia have moved into the spotlight as participants in synaptic signaling. Recent work by Bergles and colleagues extends this active role by showing that oligodendrocyte precursors cells (OPCs) in the hippocampus receive functional glutamatergic and GABAergic synapses. Synaptic signaling in these cells could provide a mechanism for activity-dependent modulation of OPC proliferation and differentiation.

摘要

神经胶质细胞作为突触信号传导的参与者已成为焦点。伯格尔斯及其同事最近的研究进一步拓展了这一积极作用，他们发现海马体中的少突胶质细胞前体细胞（OPC）能接收功能性谷氨酸能和γ-氨基丁酸能突触。这些细胞中的突触信号传导可能为OPC增殖和分化的活动依赖性调节提供一种机制。