Suppr超能文献

与右心耳起搏相比,低位房间隔起搏的电生理特性

Electrical characteristics of low atrial septum pacing compared with right atrial appendage pacing.

作者信息

de Voogt Willem G, van Mechelen Rob, van den Bos Arjan A, Scheffer Mike, van Hemel Norbert M, Levine Paul A

机构信息

St. Lucas Andreas Ziekenhuis, 1061 AE Amsterdam, The Netherlands.

出版信息

Europace. 2005 Jan;7(1):60-6. doi: 10.1016/j.eupc.2004.10.001.

Abstract

AIM

The study was designed to compare the electrical characteristics of atrial leads placed in the low atrial septum (LAS) with those placed in the right atrial appendage (RAA) associated with dual chamber pacing.

METHODS

In 86 patients an active-fixation (St. Jude Medical's Tendril DX model 1388T) atrial lead was positioned in RAA and in 86 patients the same model atrial lead was placed in the LAS. Pacing thresholds, sensing thresholds, impedances and the Far Field paced R-Wave (FFRW) amplitude and timing were compared at 6 weeks and at 3 and 6 months.

RESULTS

The pacing threshold did not differ between groups. Sensed voltage of the P-wave was higher in the LAS compared with the RAA at 3 and 6 months (P=0.004). Impedance was higher in the LAS at 6 weeks and 3 months (P=0.002) but this difference was no longer significant at 6 months (P=0.05). The atrial sensed FFRW voltage was significantly higher in the LAS position compared with the RAA at 3 and 6 months follow-up (P=0.0002). FFRW voltage>1 mV was seen in 87% of the RAA pacing group and in 94% of the LAS pacing group (P=ns). The time between the ventricular pacing stimulus and the sensed FFRW in the atrium, (V spike-FFRW) in RAA was longer than in LAS at all follow-up measurements (P=0.006).

CONCLUSIONS

The electrical characteristics of LAS pacing makes this alternative position in the atrium safe and feasible. Though statistical differences were found in P-wave sensing (LAS higher voltage than in the RAA) and FFRW sensing was higher in the LAS compared with the RAA this did not interfere with the clinical applicability of the LAS as alternative pacing site.

摘要

目的

本研究旨在比较置于低位房间隔(LAS)的心房电极与置于右心耳(RAA)且与双腔起搏相关的心房电极的电学特性。

方法

86例患者中,将主动固定型(圣犹达医疗公司的Tendril DX 1388T型号)心房电极置于RAA,另外86例患者将同一型号的心房电极置于LAS。在6周以及3个月和6个月时比较起搏阈值、感知阈值、阻抗以及远场起搏R波(FFRW)的幅度和时限。

结果

两组之间起搏阈值无差异。在3个月和6个月时,LAS处P波的感知电压高于RAA处(P = 0.004)。在6周和3个月时,LAS处的阻抗较高(P = 0.002),但在6个月时这种差异不再显著(P = 0.05)。在3个月和6个月随访时,LAS位置处心房感知的FFRW电压显著高于RAA处(P = 0.0002)。在RAA起搏组中87%以及LAS起搏组中94%可见FFRW电压>1 mV(P = 无显著性差异)。在所有随访测量中,RAA处心室起搏刺激与心房感知的FFRW之间的时间(V波峰 - FFRW)长于LAS处(P = 0.006)。

结论

LAS起搏的电学特性使得心房的这一替代位置安全可行。尽管在P波感知方面发现有统计学差异(LAS处电压高于RAA处),并且与RAA相比LAS处FFRW感知更高,但这并不影响LAS作为替代起搏部位的临床适用性。

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验