Griffiths R, Fernandez R
South Western Sydney Area Health Service, locked bag 7103, Liverpool BC, NSW, Australia, 2170.
Cochrane Database Syst Rev. 2005 Jan 25(1):CD004011. doi: 10.1002/14651858.CD004011.pub2.
Approximately 15% to 25% of all hospitalised patients have indwelling urethral catheters, mainly to assist clinicians to accurately monitor urine output during acute illness or following surgery, to treat urinary retention, and for investigative purposes.
The objective of this review was to determine the best strategies for the removal of catheters from patients with a short-term indwelling urethral catheter.
We searched the Cochrane Incontinence Group specialised register (searched 16 December 2002), the Cochrane Central Register of Controlled Trials (The Cochrane Library Issue 2, 2004), MEDLINE (January 1966 to 12 October 2004), EMBASE (January 1980 to 12 October 2004), CINAHL (January 1982 to 12 October 2004), Nursing Collection (January 1995 to January 2002) and reference lists of relevant articles and conference proceedings were searched. We also contacted manufacturers and researchers in the field. No language or other restrictions were applied.
All randomised and quasi-randomised controlled trials (RCTs) that compared the effects of alternative strategies for removal of short-term indwelling urethral catheters on patient outcomes were considered for inclusion in the review.
Eligibility of the trials for inclusion in the review, details of eligible trials and the methodological quality of the trials were assessed independently by two reviewers. Relative risks (RR) for dichotomous data and a weighted mean difference (WMD) for continuous data were calculated with 95% confidence intervals (CI). Where synthesis was inappropriate, trials were considered separately.
Eighteen trials involving a total of 1964 participants were included in the review. One trial included three treatment groups. In eight RCTs amongst 1020 people, removal at midnight was associated with large volumes of urine at first void, longer times to first void, and shorter lengths of hospitalisation. There was no significant difference in need for recatheterisation, although recatheterisation after removal at night was more likely to be during working hours. In eight trials amongst 822 participants early rather than delayed catheter removal was associated with shorter hospitalisation, but the estimates of other differences were all imprecise. In three trials involving 234 participants the data were too few to assess differential effects of catheter clamping compared with free drainage prior to withdrawal. No eligible trials compared flexible with fixed duration of catheterisation, or assessed prophylactic alpha sympathetic blocker drugs prior to catheter removal.
AUTHORS' CONCLUSIONS: There is suggestive but inconclusive evidence of a benefit from midnight removal of the indwelling urethral catheter. There are resource implications but the magnitude of these is not clear from the trials. The evidence also suggests shorter hospital stay after early rather than delayed catheter removal but the effects on other outcomes are unclear. There is little evidence on which to judge other aspects of management, such as catheter clamping.
所有住院患者中约15%至25%留置尿道导管,主要用于协助临床医生在急性疾病期间或手术后准确监测尿量、治疗尿潴留以及用于检查目的。
本综述的目的是确定从短期留置尿道导管患者中拔除导管的最佳策略。
我们检索了Cochrane尿失禁组专门注册库(2002年12月16日检索)、Cochrane对照试验中央注册库(《Cochrane图书馆》2004年第2期)、MEDLINE(1966年1月至2004年10月12日)、EMBASE(1980年1月至2004年10月12日)、CINAHL(1982年1月至2004年10月12日)、护理文献集(1995年1月至2002年1月),并检索了相关文章和会议论文的参考文献列表。我们还联系了该领域的制造商和研究人员。未施加语言或其他限制。
所有比较拔除短期留置尿道导管的替代策略对患者结局影响的随机和半随机对照试验(RCT)均被考虑纳入本综述。
两名综述员独立评估试验纳入本综述的资格、合格试验的详细信息以及试验的方法学质量。计算二分数据的相对风险(RR)和连续数据的加权平均差(WMD),并给出95%置信区间(CI)。若合并分析不恰当,则分别考虑各个试验。
本综述纳入了18项试验,共1964名参与者。一项试验包括三个治疗组。在1020人中的8项RCT中,午夜拔除导管与首次排尿时尿量多、首次排尿时间长以及住院时间短相关。再次插管的需求无显著差异,尽管夜间拔除后再次插管更可能发生在工作时间。在822名参与者中的8项试验中,早期而非延迟拔除导管与住院时间短相关,但其他差异的估计均不精确。在涉及234名参与者的3项试验中,数据过少,无法评估拔除前夹闭导管与自由引流相比的差异效果。没有合格试验比较灵活与固定的导管留置时间,或在拔除导管前评估预防性α交感神经阻滞剂药物。
有提示性但不确定的证据表明午夜拔除留置尿道导管有益。这会涉及资源问题,但试验中这些问题的严重程度尚不清楚。证据还表明早期而非延迟拔除导管后住院时间较短,但对其他结局的影响尚不清楚。几乎没有证据可用于判断管理的其他方面,如导管夹闭。