医学结局研究睡眠量表的心理测量学特性。

Psychometric properties of the Medical Outcomes Study Sleep measure.

作者信息

Hays Ron D, Martin Susan A, Sesti Anne M, Spritzer Karen L

机构信息

UCLA Department of Medicine, Division of General Internal Medicine and Health Services Research, 911 Broxton Plaza, Los Angeles, CA 90095-1736, USA.

出版信息

Sleep Med. 2005 Jan;6(1):41-4. doi: 10.1016/j.sleep.2004.07.006. Epub 2004 Nov 11.

DOI:10.1016/j.sleep.2004.07.006

PMID:15680294

Abstract

BACKGROUND AND PURPOSE

Sleep is an active and highly organized biological process that is an important component of life. Self-report measures of sleep provide information that can be useful for characterizing the quality of sleep in subgroups of the population. A 12-item self-report sleep measure, the Medical Outcomes Study Sleep measure, was developed and evaluated previously in a sample of 3445 individuals with chronic illness.

PATIENTS AND METHODS

In this study, we evaluate the psychometric properties of the MOS Sleep measure in a nationally representative sample of 1011 US adults aged 18 and older and in a sample of 173 adults with neuropathic pain participating in a clinical drug trial.

RESULTS

The average age of the general population sample was 46; 51% were female and 81% were white. The average age of the sample of adults with neuropathic pain was 72; 53% were female and 95% were white. Internal consistency reliability estimates for the MOS Sleep scales were 0.73 or higher, with the exception of the daytime somnolence scale in the US general population, which was 0.63. At baseline of the clinical trial, the neuropathic pain patients reported significantly more sleep disturbance and daytime somnolence, as well as less quantity and adequacy of sleep than patients in the general US population. The MOS Sleep scales were found to be responsive to change in the clinical trial with statistically significant improvements observed after administration of pregabalin for sleep disturbance (standardized response mean, SRM=-0.76, P=0.0007), shortness of breath (SRM=-0.20, P=0.0302), sleep adequacy (SRM=0.57, P=0.0014), sleep quantity (SRM=0.55, P=0.0086), and sleep problems (SRM=-0.62, P=0.0036).

CONCLUSIONS

This study provides further support for the reliability and validity of the MOS Sleep measure. The instrument can be used to assess important aspects of sleep perceived by adults in the general population or participating in clinical studies.

摘要

背景与目的

睡眠是一个活跃且高度有序的生物过程，是生命的重要组成部分。睡眠的自我报告测量方法可提供有助于描述特定人群亚组睡眠质量的信息。此前，在3445例慢性病患者样本中开发并评估了一项包含12个条目的自我报告睡眠测量方法——医学结局研究睡眠测量法（Medical Outcomes Study Sleep measure）。

患者与方法

在本研究中，我们在一个包含1011名18岁及以上美国成年人的全国代表性样本以及一个参与临床药物试验的173例神经性疼痛成年患者样本中，评估了医学结局研究睡眠测量法的心理测量特性。

结果

普通人群样本的平均年龄为46岁；51%为女性，81%为白人。神经性疼痛成年患者样本的平均年龄为72岁；53%为女性，95%为白人。医学结局研究睡眠量表的内部一致性信度估计值为0.73或更高，但美国普通人群中的日间嗜睡量表除外，其值为0.63。在临床试验基线时，神经性疼痛患者报告的睡眠障碍和日间嗜睡情况显著多于美国普通人群中的患者，睡眠数量和充足度也更低。研究发现，医学结局研究睡眠量表对临床试验中的变化有反应，服用普瑞巴林后，睡眠障碍（标准化反应均值，SRM = -0.76，P = 0.0007）、呼吸急促（SRM = -0.20，P = 0.0302）、睡眠充足度（SRM = 0.57，P = 0.0014）、睡眠数量（SRM = 0.55，P = 0.0086）和睡眠问题（SRM = -0.62，P = 0.0036）均有统计学意义上的显著改善。