Rawls Renard A, Vega Kenneth J
University of Florida Health Sciences Center at Jacksonville, Jacksonville, FL 32209, USA.
J Clin Gastroenterol. 2005 Feb;39(2):144-51.
Viral hepatitis continues as an important public health concern in the United States. Available data indicate that acute and chronic viral hepatitis remains an important cause of morbidity and mortality in this country despite the availability of immunization for hepatitis A and B and pharmacologic therapy for chronic hepatitis B and C. Minority populations within the United States are disproportionately affected by acute and chronic viral hepatitis. Many diseases, for example, Barrett's esophagus, affect ethnic groups differently. Viral hepatitis A, B, and C may demonstrate ethnic variation with regard to their epidemiology, natural history, clinicopatholgic findings, complications, and treatment outcomes. This report will review the literature regarding these areas in hepatitis A, B, and C among the African American, Hispanic American, and Native American populations of the United States.
在美国,病毒性肝炎仍是一个重要的公共卫生问题。现有数据表明,尽管有甲型和乙型肝炎疫苗以及针对慢性乙型和丙型肝炎的药物治疗,但急慢性病毒性肝炎在美国仍然是发病和死亡的重要原因。美国的少数族裔受急慢性病毒性肝炎的影响尤为严重。许多疾病,例如巴雷特食管,对不同种族群体的影响也有所不同。甲型、乙型和丙型病毒性肝炎在流行病学、自然史、临床病理表现、并发症及治疗结果等方面可能存在种族差异。本报告将回顾有关美国非裔、西班牙裔和美国原住民人群中甲型、乙型和丙型肝炎这些领域的文献。