Ali Mohammed, Asefaw Teklehaimanot, Byass Peter, Beyene Hagos, Pedersen F Karup
TDA IMCI Project, PO Box 756, Mekelle, Tigrai, Ethiopia.
Bull World Health Organ. 2005 Jan;83(1):27-33. Epub 2005 Jan 21.
More than 10 million children die each year mostly from preventable causes and particularly in developing countries. WHO guidelines for the Integrated Management of Childhood Illness (IMCI) are intended to reduce childhood mortality and are being implemented in Ethiopia. As well as specific clinical interventions, the role of the community in understanding and acting on childhood sickness is an important factor in improving survival. This trial sought to assess the effect on survival of community-based health promotion activities.
Two districts in northern Ethiopia were studied, each with a random sample of more than 4000 children less than 5 years old. Regular six-monthly visits were made to document deaths among children. After the first year, communities in one district were educated about issues of good childcare and caring for sick children while the other district received this information only after the trial ended.
Although overall mortality was higher in the post-intervention period, most of the increase was seen in the control area. A Cox proportional hazards model gave an adjusted hazard ratio of 0.66 (95% confidence interval = 0.46-0.95) for the intervention area compared with the control area in the post-intervention period, with no significant pre-intervention difference. Significant survival advantages were found for females, children of younger fathers, those with married parents, those living in larger households, and those whose nearest health facility was a health centre. For all of the children who died, only 44% of parents or caregivers had sought health care before the child's death.
This non-specific community-based public health intervention, as an addition to IMCI strategies in local health facilities, appears to have significantly reduced childhood mortality in these communities. The possibility that such interventions may not effectively reach certain social groups (for example single parents) is an important consideration for implementation of similar strategies in future. The synergy between community awareness and the availability of effective peripheral health services is also an issue that needs further exploration.
每年有超过1000万儿童死亡,主要死于可预防的原因,尤其在发展中国家。世界卫生组织的儿童疾病综合管理(IMCI)指南旨在降低儿童死亡率,目前正在埃塞俄比亚实施。除了特定的临床干预措施外,社区在理解儿童疾病并采取行动方面的作用是提高生存率的一个重要因素。本试验旨在评估基于社区的健康促进活动对生存率的影响。
对埃塞俄比亚北部的两个地区进行了研究,每个地区随机抽取了4000多名5岁以下儿童。每六个月定期走访以记录儿童死亡情况。第一年结束后,对一个地区的社区进行了关于良好儿童保育和照顾患病儿童问题的教育,而另一个地区仅在试验结束后才收到此信息。
尽管干预后期的总体死亡率较高,但大部分增加出现在对照地区。在干预后期,与对照地区相比,干预地区的Cox比例风险模型得出的调整后风险比为0.66(95%置信区间=0.46-0.95),干预前无显著差异。发现女性、父亲较年轻的儿童、父母已婚的儿童、生活在大家庭中的儿童以及最近的医疗设施为健康中心的儿童具有显著的生存优势。在所有死亡儿童中,只有44%的父母或照顾者在孩子死亡前寻求过医疗护理。
作为当地医疗机构IMCI策略的补充,这种非特定的基于社区的公共卫生干预措施似乎显著降低了这些社区的儿童死亡率。此类干预措施可能无法有效惠及某些社会群体(例如单亲家庭)的可能性是未来实施类似策略时的一个重要考虑因素。社区意识与有效的周边医疗服务可用性之间的协同作用也是一个需要进一步探索的问题。