一种用于研究人类牙釉质再矿化和脱矿行为的灵活快速的pH循环程序。

A flexible and rapid pH cycling procedure for investigations into the remineralisation and demineralisation behaviour of human enamel.

作者信息

Robinson C, Kirkham J, Baverstock A C, Shore R C

机构信息

Department of Oral Biology, School of Dentistry, University of Leeds, UK.

出版信息

Caries Res. 1992;26(1):14-7. doi: 10.1159/000261419.

DOI:10.1159/000261419

PMID:1568232

Abstract

A rapid and flexible model system has been developed to study human enamel behaviour under conditions of oscillating pH similar to those experienced in the mouth. The model uses realistic time intervals and operates at in vivo temperatures (35-37 degrees C). Mineral loss or gain is measured quantitatively on a volume basis. Results indicate that for single 1-day periods with three 20-min exposures to acid, 1% v/v of enamel mineral was lost. These results, together with the histological appearance of the tissue, are in close agreement with previous studies of enamel caries.

摘要

已开发出一种快速且灵活的模型系统，用于研究在类似于口腔中经历的振荡pH条件下人类牙釉质的行为。该模型使用实际的时间间隔，并在体内温度（35 - 37摄氏度）下运行。基于体积定量测量矿物质的损失或增加。结果表明，在单次为期1天的时间段内，牙釉质有三次20分钟的酸暴露，1%（v/v）的牙釉质矿物质会流失。这些结果与组织的组织学外观一起，与先前关于牙釉质龋的研究密切一致。