Tusell J M, Andaluz A, Prandi D, Costa C, García F
Department of Animal Medicine and Surgery, Faculty of Veterinary Medicine, Autonomous University of Barcelona, Bellaterra, Barcelona 08193, Spain.
Vet J. 2005 Jan;169(1):108-12. doi: 10.1016/j.tvjl.2004.01.030.
The main purpose of this study was to demonstrate that the use of epidural anaesthesia-analgesia reduces the amount of propofol necessary to maintain surgical anaesthesia in dogs during ovariohysterectomy. The study was carried out on 28 bitches undergoing ovariohysterectomy with general anaesthesia using an intravenous infusion of propofol. Dogs were allocated to one of two groups. Group 1 received systemic buprenorphine together with epidural analgesia using lidocaine and buprenophine, and in Group 2 systemic buprenorphine only was given. The mean propofol infusion rate was significantly lower in dogs with epidural analgesia (P < 0.0001). In addition, the mean endotracheal extubation time was significantly longer in dogs with epidural analgesia (P < 0.0001). No significant differences were detected in any of the physiological parameters measured.
本研究的主要目的是证明在犬卵巢子宫切除术期间，使用硬膜外麻醉镇痛可减少维持手术麻醉所需的丙泊酚用量。该研究对28只接受卵巢子宫切除术并采用丙泊酚静脉输注进行全身麻醉的母犬进行。犬被分为两组。第1组接受全身性丁丙诺啡以及使用利多卡因和丁丙诺啡的硬膜外镇痛，第2组仅给予全身性丁丙诺啡。硬膜外镇痛的犬丙泊酚平均输注速率显著更低（P < 0.0001）。此外，硬膜外镇痛的犬平均气管拔管时间显著更长（P < 0.0001）。在所测量的任何生理参数中均未检测到显著差异。
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