Steagall Paulo V M, Simon Bradley T, Teixeira Neto Francisco J, Luna Stelio P L
Faculty of Veterinary Medicine, Department of Clinical Sciences, Université de Montréal, Saint-Hyacinthe, QC, Canada.
Department of Small Animal Clinical Sciences, College of Veterinary Medicine and Biomedical Sciences, Texas A&M University, College Station, TX, USA.
Front Vet Sci. 2017 May 12;4:68. doi: 10.3389/fvets.2017.00068. eCollection 2017.
This review aims to report an update on drugs administered into the epidural space for anesthesia and analgesia in dogs, describing their potential advantages and disadvantages in the clinical setting. Databases searched include Pubmed, Google scholar, and CAB abstracts. Benefits of administering local anesthetics, opioids, and alpha agonists into the epidural space include the use of lower doses of general anesthetics (anesthetic "sparing" effect), perioperative analgesia, and reduced side effects associated with systemic administration of drugs. However, the potential for cardiorespiratory compromise, neurotoxicity, and other adverse effects should be considered when using the epidural route of administration. When these variables are considered, the epidural technique is useful as a complementary method of anesthesia for preventive and postoperative analgesia and/or as part of a balanced anesthesia technique.
本综述旨在报告犬硬膜外腔给药用于麻醉和镇痛的最新情况,描述其在临床环境中的潜在优缺点。检索的数据库包括PubMed、谷歌学术和CAB文摘。将局部麻醉药、阿片类药物和α激动剂注入硬膜外腔的益处包括使用较低剂量的全身麻醉药(麻醉“节省”效应)、围手术期镇痛以及减少与药物全身给药相关的副作用。然而,使用硬膜外给药途径时应考虑心肺功能受损、神经毒性和其他不良反应的可能性。考虑到这些变量后,硬膜外技术作为预防性和术后镇痛的辅助麻醉方法和/或作为平衡麻醉技术的一部分是有用的。