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[单剂量预防性使用抗生素在剖宫产术中的有效性:头孢噻肟与阿莫西林加克拉维酸的比较]

[The effectiveness of preventive use of antibiotics in Cesarean section with a single dose: comparison of cefotaxime with amoxicillin plus clavulanic acid].

作者信息

Köppel R, Kaehler D, Benz J

机构信息

Frauenklinik, Kantonsspital Winterthur, Schweiz.

出版信息

Geburtshilfe Frauenheilkd. 1992 Feb;52(2):113-6. doi: 10.1055/s-2007-1022964.

Abstract

The effectiveness of a single prophylactic dose of two broad spectrum antibiotics, during Caesarean section, was compared and evaluated. In 119 consecutive cases at the Cantonal Hospital in Winterthur, Switzerland, either 1 g i.v. cefotaxime or 1,2 g amoxicillin plus clavulanic acid were administered after clamping the umbilical cord during Caesarean section. The study shows that single dose prophylaxis of either regimen provides adequate cover in preventing morbidity in Caesarean section, in both high-risk and low-risk groups.

摘要

对剖宫产术中单次预防性使用两种广谱抗生素的有效性进行了比较和评估。在瑞士温特图尔州立医院连续119例病例中,剖宫产术中在脐带结扎后,静脉注射1克头孢噻肟或1.2克阿莫西林加克拉维酸。研究表明,两种方案的单次剂量预防在预防高危和低危组剖宫产术中的发病方面都提供了足够的覆盖。

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