静脉注射胺碘酮期间出现急性腰痛：两例报告

Acute low back pain during intravenous administration of amiodarone: a report of two cases.

作者信息

Korantzopoulos Panagiotis, Pappa Eugenia, Karanikis Pavlos, Kountouris Evaggelos, Dimitroula Vasiliki, Siogas Konstantinos

出版信息

Int J Cardiol. 2005 Feb 15;98(2):355-7. doi: 10.1016/j.ijcard.2004.01.001.

DOI:10.1016/j.ijcard.2004.01.001

PMID:15686794

Abstract

Amiodarone represents an effective antiarrhythmic drug for cardioversion of recent-onset atrial fibrillation (AF) and maintenance of sinus rhythm. We briefly describe two patients suffering from recent-onset atrial fibrillation, who experienced an acute devastating low back pain a few minutes after initiation of intravenous amiodarone loading. Notably, this side effect has not been ever reported in the medical literature. Clinicians should be aware of this reaction since prompt termination of parenteral administration leads to complete resolution.

摘要

胺碘酮是一种用于近期发作的心房颤动（AF）转复及维持窦性心律的有效抗心律失常药物。我们简要描述两名近期发作心房颤动的患者，他们在静脉注射胺碘酮负荷剂量开始几分钟后出现急性严重腰痛。值得注意的是，这种副作用在医学文献中从未有过报道。临床医生应知晓这种反应，因为及时终止胃肠外给药可使症状完全缓解。