Akay Kamil Melih, Izci Yusuf, Baysefer Alper, Atabey Cem, Kismet Erol, Timurkaynak Erdener
Department of Neurosurgery, Gulhane Military Medical Academy, TR-06018 Etlik-Ankara, Turkey.
Pediatr Neurosurg. 2004 Sep-Oct;40(5):220-5. doi: 10.1159/000082295.
Cerebellar tumors in childhood are generally associated with a favorable outcome if they are managed appropriately. 27 cases of pediatric cerebellar tumors, operated over a 7-year period, are presented. Histopathological diagnoses were as follows: pilocytic astrocytoma (48.2%); medulloblastoma (22.2%); ependymoma (18.5%); fibrillary astrocytoma grade III (3.7%); cystic oligodendroglioma (3.7%), and hemangioblastoma (3.7%). Microscopic gross total resection was achieved in 16 (59.3%) of 27 cases. The total removal of pediatric cerebellar tumors without neurological deficit is possible with appropriate microsurgical techniques excluding brain stem invasion. The follow-up periods must be shorter if brain stem invasion exists. Radiotherapy and chemotherapy are the adjuvant therapies according to the pathological diagnosis and the patient's age.
儿童小脑肿瘤如果得到恰当治疗,一般预后良好。本文报告了7年间手术治疗的27例儿童小脑肿瘤病例。组织病理学诊断如下:毛细胞型星形细胞瘤(48.2%);髓母细胞瘤(22.2%);室管膜瘤(18.5%);III级纤维型星形细胞瘤(3.7%);囊性少突胶质细胞瘤(3.7%),以及血管母细胞瘤(3.7%)。27例中有16例(59.3%)实现了显微镜下肉眼全切。采用适当的显微外科技术,在不侵犯脑干的情况下,有可能完全切除儿童小脑肿瘤且不造成神经功能缺损。如果存在脑干侵犯,随访期必须缩短。根据病理诊断和患者年龄,放疗和化疗为辅助治疗方法。