Department of Experimental Psychology, Universiteit Gent, Ghent, Belgium.
Eur J Paediatr Neurol. 2012 Sep;16(5):434-42. doi: 10.1016/j.ejpn.2011.12.013. Epub 2012 Jan 18.
Mutism and Subsequent Dysarthria (MSD) and the Posterior Fossa Syndrome (PFS) have become well-recognized clinical entities which may develop after resection of cerebellar tumours. However, speech characteristics following a period of mutism have not been documented in much detail. This study carried out a perceptual speech analysis in 24 children and adolescents (of whom 12 became mute in the immediate postoperative phase) 1-12.2 years after cerebellar tumour resection. The most prominent speech deficits in this study were distorted vowels, slow rate, voice tremor, and monopitch. Factors influencing long-term speech disturbances are presence or absence of postoperative PFS, the localisation of the surgical lesion and the type of adjuvant treatment. Long-term speech deficits may be present up to 12 years post-surgery. The speech deficits found in children and adolescents with cerebellar lesions following cerebellar tumour surgery do not necessarily resemble adult speech characteristics of ataxic dysarthria.
缄默和随后的构音障碍（MSD）和后颅窝综合征（PFS）已成为众所周知的临床实体，可能在小脑肿瘤切除后发展。然而，缄默期后的言语特征并未详细记录。本研究对 24 名儿童和青少年（其中 12 名在术后即刻阶段出现缄默）进行了感知言语分析，这些患者在小脑肿瘤切除后 1-12.2 年。本研究中最突出的言语缺陷是元音扭曲、语速慢、语音震颤和单音。影响长期言语障碍的因素包括术后是否存在 PFS、手术病变的定位和辅助治疗的类型。长期言语缺陷可能会持续 12 年以上。小脑肿瘤手术后小脑病变患儿和青少年的言语缺陷不一定与共济失调性构音障碍的成人言语特征相似。
