Chieregatti Evelina, Meldolesi Jacopo
Department of Neuroscience, Vita-Salute San Raffaele University, Center of Excellence in Cellular Pathophysiology, San Raffaele Scientific Institute, Via Olgettina 58, 20132 Milan, Italy.
Nat Rev Mol Cell Biol. 2005 Feb;6(2):181-7. doi: 10.1038/nrm1572.
Regulated exocytosis is a process in which the membranes of cytoplasmic organelles fuse with the plasma membrane in response to stimulation. In many cases (secretory exocytoses), the process functions to secrete specific products that are segregated in the organelle lumen (for example, neurotransmitters, hormones and enzymes) to the extracellular space. In other cases ('non-secretory exocytoses'), it functions to transfer the organelle membrane and its components to the cell surface. Here, the general properties of non-secretory exocytoses are discussed.
受调控的胞吐作用是一种过程，在该过程中，细胞质细胞器的膜会响应刺激与质膜融合。在许多情况下（分泌性胞吐作用），该过程的功能是将分隔在细胞器腔内的特定产物（例如神经递质、激素和酶）分泌到细胞外空间。在其他情况下（“非分泌性胞吐作用”），它的功能是将细胞器膜及其成分转移到细胞表面。在此，将讨论非分泌性胞吐作用的一般特性。
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