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[骨软骨黏液样纤维瘤:儿童罕见的良性骨肿瘤]

[Chondromyxoid fibroma of bone: a rare benign bone tumor in children].

作者信息

Rouas L, Malihy A, Cherradi N, Lamalmi N, Alhamany Z

机构信息

Service d'Anatomie-Cytologie Pathologique, Hôpital d'Enfants, Rabat, Maroc.

出版信息

Rev Med Brux. 2004 Dec;25(6):521-4.

Abstract

Chondromyxoid fibroma is a rare benign tumor that is typically found in the metaphyseal ends of long tubular bones, such as the tibia. The radiographic appearances are those of a single, lytic lesion with lobulated margins, septations, cortical expansion and a sclerotic rim. The classic histological feature of a chondromyxoid fibroma is stellate or spindle-shaped cells arranged in lobules in a myxoid or chondroid background. Two cases are presented here: 8, and 12-year-old patients, both with lesions in the proximal tibia. The first case showed an unusual feature: it was diaphyseal chondromyxoid fibroma. In the second case, the lesion was metaphyso-diaphyseal. The differential diagnosis includes chondroblastoma, myxoma, aneurysmal cyst as well as chondrosarcoma. A surgical conservative treatment with complete excision is recommended even in case of recurrence.

摘要

软骨黏液样纤维瘤是一种罕见的良性肿瘤,通常见于长管状骨的干骺端,如胫骨。影像学表现为单个溶骨性病变,边缘呈分叶状,有分隔、皮质膨胀及硬化边缘。软骨黏液样纤维瘤的典型组织学特征是星状或梭形细胞在黏液样或软骨样背景中呈小叶状排列。本文介绍两例:分别为8岁和12岁患者,均有胫骨近端病变。第一例显示出一个不寻常的特征:它是骨干软骨黏液样纤维瘤。第二例病变位于干骺 - 骨干。鉴别诊断包括软骨母细胞瘤、黏液瘤、动脉瘤样骨囊肿以及软骨肉瘤。即使复发也建议进行完整切除的手术保守治疗。

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