Dimitroulis George
Department of Surgery, St. Vincent's Hospital Melbourne, University of Melbourne, Melbourne, Australia.
J Oral Maxillofac Surg. 2005 Feb;63(2):173-8. doi: 10.1016/j.joms.2004.06.051.
The aim of this retrospective clinical study was to review the outcomes of temporomandibular joint (TMJ) discectomy with autogenous dermis used as an immediate interpositional graft in patients with advanced internal derangement of the TMJ.
Thirty-five joints in 29 patients who presented with advanced internal derangement of the TMJ with degenerate and irreparable discs were identified and included in the study. All patients underwent a TMJ arthrotomy (including 6 bilateral TMJ procedures) that involved removal of the disc (discectomy) and immediate replacement with autogenous dermis graft. Patients were followed up for an average of 2 years.
There was a mean +6.7-mm improvement in maximum interincisal opening, a 66% mean improvement in pain ( P < .001), and a 42% mean improvement in function ( P < .05) after TMJ discectomy with immediate dermis graft replacement. After an average follow-up period of 24.6 months, patients reported good to excellent improvement in their TMJ symptoms in 30 of the 35 joints (85.7%). All patients showed radiologic evidence of varying degrees of condylar remodeling at 6 months or later after surgery. Of the 7 patients who had magnetic resonance imaging (MRI) performed at 6 months or later after surgery, none showed any radiologic evidence of the dermis graft. No clinical evidence of joint sounds such as crepitus was found in 33 of the 35 operated joints.
This study found that TMJ discectomy can have a significant positive effect on the management of patients with advanced internal derangement of the TMJ who fail to respond to less invasive measures such as splint therapy and TMJ arthroscopy. However, the only advantage of dermis grafts over no grafts seems to be that it can minimize or eliminate joint sounds such as crepitus in the discectomized TMJ. In this study, the dermis grafts did not prevent regressive remodeling of the mandibular condyles.
本回顾性临床研究旨在评估颞下颌关节(TMJ)内紊乱晚期患者行颞下颌关节盘切除术并立即植入自体真皮作为间置物移植后的疗效。
本研究纳入29例患者共35个颞下颌关节,这些患者均表现为颞下颌关节内紊乱晚期且关节盘退变、无法修复。所有患者均接受了颞下颌关节切开术(包括6例双侧颞下颌关节手术),手术包括切除关节盘(盘切除术)并立即植入自体真皮移植物。患者平均随访2年。
颞下颌关节盘切除并立即植入真皮移植物后,平均最大切牙间开口度增加6.7mm,平均疼痛改善66%(P <.001),平均功能改善42%(P <.05)。平均随访24.6个月后,35个关节中的30个(85.7%)患者报告颞下颌关节症状有良好至极佳的改善。所有患者在术后6个月或更晚均显示有不同程度髁突重塑的影像学证据。7例患者在术后6个月或更晚进行了磁共振成像(MRI)检查,均未显示真皮移植物的任何影像学证据。35个接受手术的关节中,33个未发现有关节弹响等临床证据。
本研究发现,对于颞下颌关节内紊乱晚期且对诸如夹板治疗和颞下颌关节镜检查等侵入性较小的措施无反应的患者,颞下颌关节盘切除术可产生显著的积极效果。然而,与不进行移植相比,真皮移植物的唯一优势似乎在于它可以减少或消除盘切除术后颞下颌关节的弹响等关节声音。在本研究中,真皮移植物并未阻止下颌髁突的退行性重塑。